Merle Roswitha, Mollenhauer Yvonne, Hajek Peter, Robanus Matthias, Hegger-Gravenhorst Christine, Honscha Walther, Käsbohrer Annemarie, Kreienbrock Lothar
Institut für Biometrie, Epidemiologie und Informationsverarbeitung, Tierärztliche Hochschule Hannover.
Berl Munch Tierarztl Wochenschr. 2013 Jul-Aug;126(7-8):318-25.
47 cattle farms with a total of 6500 cattle in one district of Northrhine-Westfalia took part in a study on the use of antibiotic substances on a voluntary basis. The veterinary application and dispensary documents (section 13 TAHAV) as well as respecting farmers' documents (ANTHV) served as data sources. All consumption data of a one-year-period (1 September, 2006 until 31 August, 2007) were entered into a central database. The amount (free substances in kg) of substances were highest for beta-lactams (48%) followed by sulfonamides inc. trimethoprim (17%) and tetracyclines (11%). All in all about 39 kg free antibiotic substances were applied.The analysis of the treatment frequency showed similar figures: beta-lactams were used in 35% of all cattle treatments, but tetracyclines were used only in 9% of the treatments. The highest number of therapies took place against udder diseases (45% of all free substances applied, 56% of all treatment units). The therapy frequency is the average number of applied treatment units (treatment days and number of substances) per age or production group within a certain time period and population. It corresponds basically to the DDD (Defined Daily Dose) of the Netherlands as well as to the ADD (Defined Animal Daily Dose) of Denmark, although these values cannot be compared directly because of different calculation methods. Within a period of 100 days every dairy calf in the study farms achieved 0.7, every dairy cow 0.9 (including teat sealer = one day) and every fattening cattle 0.01 treatment units averagely.
北莱茵 - 威斯特法伦州一个地区的47个养牛场,共6500头牛,自愿参与了一项关于抗生素物质使用的研究。兽医应用和药房文件(《动物健康与福利法》第13节)以及养殖户文件(《动物健康与福利法》)作为数据来源。将一年期间(2006年9月1日至2007年8月31日)的所有使用数据录入一个中央数据库。β - 内酰胺类药物的使用量(以千克计的游离物质)最高(48%),其次是磺胺类药物(包括甲氧苄啶,17%)和四环素类药物(11%)。总计约39千克游离抗生素物质被使用。治疗频率分析显示了类似的数据:β - 内酰胺类药物用于所有牛治疗的35%,但四环素类药物仅用于9%的治疗。治疗次数最多的是针对乳房疾病(占所有游离物质使用量的45%,占所有治疗单元的56%)。治疗频率是指在特定时间段和种群内,每个年龄或生产组应用的治疗单元(治疗天数和物质数量)的平均数。它基本上对应于荷兰的限定日剂量(DDD)以及丹麦的限定动物日剂量(ADD),尽管由于计算方法不同,这些值不能直接比较。在100天的时间段内,研究农场中的每头奶牛犊平均达到0.7个治疗单元,每头奶牛平均达到0.9个治疗单元(包括乳头封闭剂 = 一天),每头育肥牛平均达到0.01个治疗单元。