Patel Punit Vaibhav, Gujjari Sheela Kumar
Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University (B.H.U.) , Varanasi,-05, U.P., India .
J Clin Diagn Res. 2013 Jun;7(6):1239-43. doi: 10.7860/JCDR/2013/4963.3039. Epub 2013 Jun 1.
We are presenting 2 cases where ozone therapy was used in the form of ozonated oil on an exophytic fibrous gingival lesion. A 42-years female patient was selected, who presented with a mild to moderately painful, exophytic, fibrous lesion on the upper anterior gingiva. This gingival lesion was treated with 2ml of ozonated oil, thrice daily for one week. After the ozone therapy, the postoperative outcomes were measured and analyzed. Finally, the lesion was subjected to an excisional biopsy and a histopathological evaluation. After the ozone therapy, the patient revealed that there was less pain. On examination of the lesion, an improvement was observed in the clinical sign of the inflammation and also a reduction in the surface ulceration. During the final biopsy, less bleeding was observed. The morphometrical analysis showed a reduction in the size of the lesion. The histopathological analysis showed a reduction in the collagen fibres and in the inflammatory cells in the connective tissue stroma. Topical ozone therapy provides potential benefits for the treatment of exophytic gingival lesions. The observed benefits in present case report needs to be verified in future with well-controlled clinical trials.
我们报告2例使用臭氧油治疗外生性纤维性牙龈病变的病例。选择了一名42岁女性患者，其上前牙龈出现轻度至中度疼痛的外生性纤维性病变。用2毫升臭氧油治疗该牙龈病变，每日3次，持续1周。臭氧治疗后，对术后结果进行测量和分析。最后，对病变进行切除活检和组织病理学评估。臭氧治疗后，患者表示疼痛减轻。检查病变时，观察到炎症的临床体征有所改善，表面溃疡也有所减少。在最后活检时，观察到出血较少。形态学分析显示病变大小减小。组织病理学分析显示结缔组织基质中的胶原纤维和炎性细胞减少。局部臭氧治疗为外生性牙龈病变的治疗提供了潜在益处。本病例报告中观察到的益处需要在未来通过严格控制的临床试验进行验证。
