Rachinger Michael, Volland Sonja, Meinhardt Friedhelm, Daniel Rolf, Liesegang Heiko
Georg-August University Göttingen, Institute of Microbiology and Genetics, Department of Genomic and Applied Microbiology & Göttingen Genomics Laboratory, Göttingen, Germany.
Genome Announc. 2013 Aug 1;1(4):e00525-13. doi: 10.1128/genomeA.00525-13.
Strains of the species Bacillus licheniformis are widely used in biotechnology for the production of enzymes and antibiotics (M. Schallmey, A. Singh, and O. P. Ward, Can. J. Microbiol. 50:1-17, 2004). However, research and application of B. licheniformis strains are adversely affected by poor genetic accessibility. Thus, for a closer inspection of natural competence in B. licheniformis, the genome of strain 9945A, of which derivatives are known to be naturally competent (C. B. Thorne and H. B. Stull, J. Bacteriol. 91:1012-1020, 1966), was completely sequenced and manually annotated.
地衣芽孢杆菌（Bacillus licheniformis）菌株在生物技术领域被广泛用于生产酶和抗生素（M. 沙尔梅、A. 辛格和O. P. 沃德，《加拿大微生物学杂志》50:1 - 17，2004年）。然而，地衣芽孢杆菌菌株的研究和应用受到遗传可及性差的不利影响。因此，为了更深入地研究地衣芽孢杆菌的自然感受态，对9945A菌株的基因组进行了全序列测定和人工注释，已知该菌株的衍生物具有自然感受态（C. B. 索恩和H. B. 斯图尔，《细菌学杂志》91:1012 - 1020，1966年）。
