Eytan Danny
Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering and Pediatrics A, Rambam Medical Center, Haifa, Israel.
Rambam Maimonides Med J. 2011 Jul 31;2(3):e0054. doi: 10.5041/RMMJ.10054. Print 2011 Jul.
The work presented in this review describes the use of large cortical networks developing ex vivo, in a culture dish, to study principles underlying synchronization, adaptation, learning, and representation in neuronal assemblies. The motivation to study neuronal networks ex vivo is outlined together with a short description of recent results in this field. Following a short description of the experimental system, a set of basic results will be presented that concern self-organization of activity, dynamical and functional properties of neurons and networks in response to external stimulation. This short review ends with an outline of future questions and research directions.
本综述中介绍的工作描述了在培养皿中离体培养大型皮质网络，以研究神经元集合中同步、适应、学习和表征背后的原理。文中概述了离体研究神经元网络的动机，并简要介绍了该领域的最新研究成果。在简短描述实验系统之后，将展示一组关于活动的自组织、神经元和网络对外部刺激的动态及功能特性的基础研究成果。这篇简短的综述最后列出了未来的问题和研究方向。
