• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Recognition and control of the progression of age-related hearing loss.年龄相关性听力损失的进展的识别和控制。
Rejuvenation Res. 2013 Dec;16(6):475-86. doi: 10.1089/rej.2013.1435.
2
The Role of Molecular and Cellular Aging Pathways on Age-Related Hearing Loss.分子和细胞衰老途径在与年龄相关的听力损失中的作用。
Int J Mol Sci. 2024 Sep 7;25(17):9705. doi: 10.3390/ijms25179705.
3
The role of mitochondria in age-related hearing loss.线粒体在年龄相关性听力损失中的作用。
Biogerontology. 2014 Feb;15(1):13-9. doi: 10.1007/s10522-013-9475-y. Epub 2013 Nov 8.
4
The mouse as a model for age-related hearing loss - a mini-review.作为年龄相关性听力损失模型的小鼠——一篇综述短文
Gerontology. 2015;61(2):149-57. doi: 10.1159/000368399. Epub 2014 Nov 28.
5
ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation.ROS 诱导的 DNA 损伤反应导致有丝分裂后耳蜗细胞进入衰老样状态:对听力保护的意义。
Mol Neurobiol. 2019 Aug;56(8):5950-5969. doi: 10.1007/s12035-019-1493-6. Epub 2019 Jan 28.
6
Associations of Dietary Riboflavin, Niacin, and Retinol with Age-related Hearing Loss: An Analysis of Korean National Health and Nutrition Examination Survey Data.饮食核黄素、烟酸和视黄醇与年龄相关性听力损失的关联:对韩国国家健康和营养检查调查数据的分析。
Nutrients. 2019 Apr 21;11(4):896. doi: 10.3390/nu11040896.
7
Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.结节性硬化症复合物介导的 mTORC1 过度激活促进年龄相关性听力损失。
J Clin Invest. 2018 Nov 1;128(11):4938-4955. doi: 10.1172/JCI98058. Epub 2018 Sep 24.
8
Induced Short-Term Hearing Loss due to Stimulation of Age-Related Factors by Intermittent Hypoxia, High-Fat Diet, and Galactose Injection.间歇低氧、高脂饮食和半乳糖注射诱导的与年龄相关因素刺激引起的短期听力损失。
Int J Mol Sci. 2020 Sep 25;21(19):7068. doi: 10.3390/ijms21197068.
9
Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea.石榴皮提取物通过调节小鼠耳蜗中PNUTS/PP1的活性减轻D-半乳糖诱导的氧化应激和听力损失。
Neurobiol Aging. 2017 Nov;59:30-40. doi: 10.1016/j.neurobiolaging.2017.07.007. Epub 2017 Jul 25.
10
Role of antioxidants in prevention of age-related hearing loss: a review of literature.抗氧化剂在预防年龄相关性听力损失中的作用:文献综述
Eur Arch Otorhinolaryngol. 2017 Apr;274(4):1821-1834. doi: 10.1007/s00405-016-4378-6. Epub 2016 Nov 17.

引用本文的文献

1
Phytosterols reverse antiretroviral-induced hearing loss, with potential implications for cochlear aging.植物固醇可逆转抗逆转录病毒引起的听力损失,这可能对耳蜗衰老有影响。
PLoS Biol. 2023 Aug 24;21(8):e3002257. doi: 10.1371/journal.pbio.3002257. eCollection 2023 Aug.
2
Advancements in prevention and intervention of sensorineural hearing loss.感音神经性听力损失的预防与干预进展
Ther Adv Chronic Dis. 2022 Jun 27;13:20406223221104987. doi: 10.1177/20406223221104987. eCollection 2022.
3
Construction and Evaluation of a High-Frequency Hearing Loss Screening Tool for Community Residents.构建并评估适用于社区居民的高频听力损失筛查工具。
Int J Environ Res Public Health. 2021 Nov 23;18(23):12311. doi: 10.3390/ijerph182312311.
4
Improved Sensitivity of Digits-in-Noise Test to High-Frequency Hearing Loss.数字噪声测试对高频听力损失的敏感性提高
Ear Hear. 2021 May/Jun;42(3):565-573. doi: 10.1097/AUD.0000000000000956.
5
The Listening Network and Cochlear Implant Benefits in Hearing-Impaired Adults.听力网络与人工耳蜗对成年听力障碍者的益处
Front Aging Neurosci. 2021 Feb 25;13:589296. doi: 10.3389/fnagi.2021.589296. eCollection 2021.
6
Induced Short-Term Hearing Loss due to Stimulation of Age-Related Factors by Intermittent Hypoxia, High-Fat Diet, and Galactose Injection.间歇低氧、高脂饮食和半乳糖注射诱导的与年龄相关因素刺激引起的短期听力损失。
Int J Mol Sci. 2020 Sep 25;21(19):7068. doi: 10.3390/ijms21197068.
7
Preventing presbycusis in mice with enhanced medial olivocochlear feedback.增强内侧橄榄耳蜗反馈预防小鼠 presbycusis。
Proc Natl Acad Sci U S A. 2020 May 26;117(21):11811-11819. doi: 10.1073/pnas.2000760117. Epub 2020 May 11.
8
Making the Case for Research on Disease-Modifying Treatments to Tackle Post-lingual Progressive Sensorineural Hearing Loss.为针对语后渐进性感音神经性听力损失的疾病修饰治疗研究提供依据。
Front Neurol. 2020 Apr 21;11:290. doi: 10.3389/fneur.2020.00290. eCollection 2020.
9
Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.丝裂原活化蛋白激酶磷酸酶 1(DUSP1)缺失加速进行性听力损失。
Elife. 2019 Apr 2;8:e39159. doi: 10.7554/eLife.39159.
10
DAPT mediates atoh1 expression to induce hair cell-like cells.双重抗血小板治疗(DAPT)介导无调性基因1(atoh1)表达以诱导毛细胞样细胞。
Am J Transl Res. 2016 Feb 15;8(2):634-43. eCollection 2016.

本文引用的文献

1
Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis.褪黑素抑制半胱天冬酶-1/细胞色素 c/半胱天冬酶-3 细胞死亡途径,抑制 MT1 受体丢失并延缓肌萎缩侧索硬化症小鼠模型的疾病进展。
Neurobiol Dis. 2013 Jul;55:26-35. doi: 10.1016/j.nbd.2013.03.008. Epub 2013 Mar 26.
2
Linking the metabolic state and mitochondrial DNA in chronic disease, health, and aging.连接慢性病、健康与衰老中的代谢状态和线粒体DNA。
Diabetes. 2013 Mar;62(3):672-8. doi: 10.2337/db12-1203.
3
Mechanisms that regulate stem cell aging and life span.调控干细胞衰老和寿命的机制。
Cell Stem Cell. 2013 Feb 7;12(2):152-65. doi: 10.1016/j.stem.2013.01.001.
4
Age-related hearing loss in rhesus monkeys is correlated with cochlear histopathologies.恒河猴的年龄相关性听力损失与耳蜗组织病理学变化相关。
PLoS One. 2013;8(2):e55092. doi: 10.1371/journal.pone.0055092. Epub 2013 Feb 4.
5
Adenovector-mediated gene delivery to human umbilical cord mesenchymal stromal cells induces inner ear cell phenotype.腺病毒载体介导的基因传递至人脐带间充质基质细胞可诱导内耳细胞表型。
Cell Reprogram. 2013 Feb;15(1):43-54. doi: 10.1089/cell.2011.0097.
6
Intracerebral neural stem cell transplantation improved the auditory of mice with presbycusis.脑内神经干细胞移植改善了老年性聋小鼠的听力。
Int J Clin Exp Pathol. 2013;6(2):230-41. Epub 2013 Jan 15.
7
Cell-type-specific roles of Na+/K+ ATPase subunits in Drosophila auditory mechanosensation.果蝇听觉机械感觉中 Na+/K+ATPase 亚基的细胞类型特异性作用。
Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):181-6. doi: 10.1073/pnas.1208866110. Epub 2012 Dec 17.
8
Mitochondrial disorders as windows into an ancient organelle.线粒体疾病:揭示古老细胞器的窗口
Nature. 2012 Nov 15;491(7424):374-83. doi: 10.1038/nature11707.
9
Restoration of auditory evoked responses by human ES-cell-derived otic progenitors.人胚胎干细胞来源的耳前体细胞对听觉诱发电位的修复作用。
Nature. 2012 Oct 11;490(7419):278-82. doi: 10.1038/nature11415. Epub 2012 Sep 12.
10
Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition.减少磷脂酰肌醇 4,5-二磷酸的合成会损害内耳 Ca2+信号转导和高频听力的获得。
Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14013-8. doi: 10.1073/pnas.1211869109. Epub 2012 Aug 13.

年龄相关性听力损失的进展的识别和控制。

Recognition and control of the progression of age-related hearing loss.

机构信息

Department of Otolaryngology Head and Neck Surgery, the Second Xiangya Hospital, Central South University , Changsha, Hunan, P.R. China .

出版信息

Rejuvenation Res. 2013 Dec;16(6):475-86. doi: 10.1089/rej.2013.1435.

DOI:10.1089/rej.2013.1435
PMID:23915327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3869427/
Abstract

Recent breakthroughs have provided notable insights into both the pathogenesis and therapeutic strategies for age-related hearing loss (ARHL). Simultaneously, these breakthroughs enhance our knowledge about this neurodegenerative disease and raise the question of whether the disorder is preventable or even treatable. Discoveries relating to ARHL have revealed a unique link between ARHL and the underlying pathologies. Therefore, we need to better understand the pathogenesis or the mechanism of ARHL and learn how to take full advantage of various therapeutic strategies to prevent the progression of ARHL.

摘要

最近的突破为年龄相关性听力损失(ARHL)的发病机制和治疗策略提供了重要的见解。同时,这些突破也增加了我们对这种神经退行性疾病的了解,并提出了一个问题,即这种疾病是否可以预防,甚至是否可以治疗。与 ARHL 相关的发现揭示了 ARHL 与潜在病理之间的独特联系。因此,我们需要更好地了解 ARHL 的发病机制或机制,并学习如何充分利用各种治疗策略来阻止 ARHL 的进展。