Department of Otolaryngology, School of Medicine, Kangwon National University, 1 Gangwondaehakgil, Chuncheon, Gangwon-do 24341, Korea.
Department of Otorhinolaryngology-Head & Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43 gil, Songpa-gu, Seoul 05505, Korea.
Nutrients. 2019 Apr 21;11(4):896. doi: 10.3390/nu11040896.
Because age-related hearing loss (ARHL) is irreversible, prevention is very important. Thus, investigating modifying factors that help prevent ARHL is critical for the elderly. Nutritional status or nutritional factors for the elderly are known to be associated with many problems related to aging. Emerging studies suggest that there was the interaction between nutrition and ARHL. We aimed to investigate the possible impact of dietary nutrients on ARHL using data from the fifth Korean National Health and Nutrition Examination Survey (KNHANES) which included 4742 subjects aged ≥ 65 years from 2010 to 2012. All participants underwent an otologic examination, audiologic evaluation, and nutritional survey. The associations between ARHL and nutrient intake were analyzed using simple and multiple regression models with complex sampling adjusted for confounding factors, such as BMI, smoking status, alcohol consumption, and history of hypertension and diabetes. Higher intake groups of riboflavin, niacin and retinol was inversely associated with ARHL prevalence (riboflavin aOR, 0.71; 95% CI, 0.54-0.94; = 0.016, niacin aOR, 0.72; 95% CI, 0.54-0.96; = 0.025, retinol aOR 0.66; 95% CI, 0.51-0.86; = 0.002, respectively). Our findings suggest the recommended intake levels of riboflavin, niacin, and retinol may help reduce ARHL in the elderly.
由于与年龄相关的听力损失（ARHL）是不可逆转的，因此预防非常重要。因此，研究有助于预防 ARHL 的调节因素对老年人至关重要。众所周知，老年人的营养状况或营养因素与许多与衰老相关的问题有关。新兴研究表明，营养与 ARHL 之间存在相互作用。我们旨在使用 2010 年至 2012 年包括 4742 名年龄≥65 岁的受试者的第五次韩国国家健康和营养检查调查（KNHANES）的数据，调查膳食营养素对 ARHL 的可能影响。所有参与者均接受了耳科检查、听力评估和营养调查。使用简单和多元回归模型，在调整了 BMI、吸烟状况、饮酒以及高血压和糖尿病病史等混杂因素后，分析了 ARHL 与营养素摄入之间的关联。核黄素、烟酸和视黄醇的摄入量较高与 ARHL 患病率呈负相关（核黄素 aOR，0.71；95%CI，0.54-0.94； = 0.016，烟酸 aOR，0.72；95%CI，0.54-0.96； = 0.025，视黄醇 aOR 0.66；95%CI，0.51-0.86； = 0.002，分别）。我们的研究结果表明，推荐的核黄素、烟酸和视黄醇摄入量可能有助于减少老年人的 ARHL。
