塞德莱克病毒（正布尼亚病毒科，布尼亚病毒属）的部分遗传特征。
Partial genetic characterization of Sedlec virus (Orthobunyavirus, Bunyaviridae).
机构信息
Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent István University, Hungária krt. 23-25, H-1143 Budapest, Hungary; Viral Zoonoses, Emerging and Vector-Borne Infections Group, Institute of Virology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210 Vienna, Austria.
出版信息
Infect Genet Evol. 2013 Oct;19:244-9. doi: 10.1016/j.meegid.2013.07.025. Epub 2013 Aug 2.
Sedlec virus (SEDV) was isolated from the blood of a reed warbler (Acrocephalus scirpaceus) in July 1984 in South Moravia, Czech Republic. In this study first genetic data of SEDV are presented which allow an estimate on its phylogenetic and taxonomic positioning within the genus Orthobunyavirus. The phylogenetic analysis of a 369 nt long stretch within the S segment (nucleocapsid protein gene and non-structural S protein gene) indicates genetic relatedness of SEDV to Leanyer virus and Simbu group viruses, while the phylogenetic tree based on 1796nt long sequences of the L segment (RNA-dependent RNA polymerase gene) demonstrates genetic relationship of SEDV to two yet unclassified orthobunyaviruses: I612045 virus (isolated in India in 1961) and Oyo virus (isolated in Nigeria in 1964). Considering the genetic distances and the phylogenetic analyses, SEDV might represent a novel serogroup of the Orthobunyavirus genus.
赛德尔溪病毒（SEDV）于 1984 年 7 月在捷克共和国南摩拉维亚的一只芦苇莺（Acrocephalus scirpaceus）血液中被分离出来。本研究首次提供了 SEDV 的遗传数据，可据此对其在正粘病毒属内的系统发育和分类定位进行估计。S 片段（核衣壳蛋白基因和非结构 S 蛋白基因）369nt 长片段的系统发育分析表明，SEDV 与 Leanyer 病毒和 Simbu 群病毒具有遗传相关性，而基于 L 片段（RNA 依赖性 RNA 聚合酶基因）1796nt 长序列的系统发育树则表明，SEDV 与两种尚未分类的正粘病毒具有遗传关系：I612045 病毒（1961 年在印度分离）和奥约病毒（1964 年在尼日利亚分离）。考虑到遗传距离和系统发育分析，SEDV 可能代表正粘病毒属的一个新血清群。
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