Mossel Eric C, Crabtree Mary B, Mutebi John-Paul, Lutwama Julius J, Borland Erin M, Powers Ann M, Miller Barry R
Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Rd., Fort Collins, CO 80521.
Department of Arbovirology, Uganda Virus Research Institute (UVRI), PO Box 49, Entebbe, Uganda.
J Med Entomol. 2017 Sep 1;54(5):1403-1409. doi: 10.1093/jme/tjx120.
A large number of arthropod-borne viruses are endemic to East Africa. As a part of the process of undertaking a systematic characterization of the mosquito fauna of Uganda, we examined mosquitoes collected from 2008 through early 2012 for known and novel viruses. In all, 8,288 mosquito pools containing 157,554 mosquitoes were tested. Twenty-nine isolations of 11 different viruses were made from mosquitoes of nine distinct species and from pools identified only to genus Culex. Identified viruses were from family Togaviridae, alphaviruses Sindbis and Babanki viruses; family Rhabdoviridae, hapaviruses Mossuril and Kamese viruses; family Flaviviridae, flaviviruses West Nile and Usutu viruses; family Phenuiviridae, phlebovirus Arumowot virus; and family Peribunyaviridae, orthobunyaviruses Witwatersrand, Pongola, and Germiston viruses. In addition, a novel orthobunyavirus, provisionally named Mburo virus, was isolated from Coquillettidia metallica (Theobald). This is the first report of Babanki, Arumowot, and Mossuril virus isolation from Uganda.
大量节肢动物传播的病毒在东非呈地方性流行。作为对乌干达蚊虫群落进行系统特征描述工作的一部分，我们检测了2008年至2012年初采集的蚊虫，以查找已知和新型病毒。总共检测了8288个蚊群，包含157554只蚊子。从9个不同蚊种以及仅鉴定到库蚊属的蚊群中分离出了11种不同病毒的29个毒株。鉴定出的病毒分别来自披膜病毒科的辛德毕斯病毒和班班基病毒；弹状病毒科的哈帕病毒莫苏里尔病毒和卡梅斯病毒；黄病毒科的西尼罗河病毒和乌苏图病毒；白蛉病毒科的静脉病毒阿鲁莫沃特病毒；以及布尼亚病毒科的正布尼亚病毒威特沃特斯兰德病毒、庞戈拉病毒和杰米斯顿病毒。此外，还从金属色库蚊（西奥博尔德）中分离出一种新型正布尼亚病毒，暂命名为姆布鲁病毒。这是在乌干达首次报告分离出班班基病毒、阿鲁莫沃特病毒和莫苏里尔病毒。
