在接受血液透析的 2 型糖尿病患者中给予大剂量抗坏血酸时，葡萄糖浓度出现假性升高。
Spurious elevation of glucose concentration during administration of high dose of ascorbic acid in a patient with type 2 diabetes on hemodialysis.
机构信息
Department of Internal Medicine, Gyeongsang National University School of Medicine, 79 Gangnam-ro, Jinju 660-702, Korea.
出版信息
Yonsei Med J. 2013 Sep;54(5):1289-92. doi: 10.3349/ymj.2013.54.5.1289.
Abstract
We describe herein a case of life-threatening hypoglycemia due to spurious elevation of glucose concentration during the administration of ascorbic acid in a type 2 diabetic patient. A 31-year-old female was admitted for proliferative diabetic retinopathy treatment and prescribed high dose ascorbic acid. During hospitalization, she suddenly lost her consciousness and her glucose concentration was 291 mg/dL, measured using self-monitoring blood glucose (SMBG) device, while venous blood glucose concentration was 12 mg/dL. After intravenous injection of 50% glucose solution, the patient became alert. We reasoned that glucose measurement by SMBG device was interfered by ascorbic acid. Physicians should be aware of this interference; high dose ascorbic acid may cause spurious elevation of glucose concentration when measuring with SMBG devices.
摘要
我们在此描述了一例 2 型糖尿病患者在给予抗坏血酸治疗期间因葡萄糖浓度假性升高而导致严重低血糖的病例。一名 31 岁女性因增殖性糖尿病视网膜病变入院治疗并开了大剂量抗坏血酸。住院期间，她突然意识丧失，使用自我监测血糖 (SMBG) 仪测量的血糖浓度为 291mg/dL，而静脉血糖浓度为 12mg/dL。静脉注射 50%葡萄糖溶液后，患者意识清醒。我们推断 SMBG 仪的血糖测量受到了抗坏血酸的干扰。医生应注意这种干扰；当使用 SMBG 设备测量时，大剂量抗坏血酸可能导致葡萄糖浓度假性升高。
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