Quesnele Jairus J, Laframboise Michelle A, Wong Jessica J, Kim Peter, Wells Greg D
Division of Clinical Studies, Canadian Memorial Chiropractic College, Toronto, Canada.
Int J Sport Nutr Exerc Metab. 2014 Feb;24(1):14-27. doi: 10.1123/ijsnem.2013-0007. Epub 2013 Aug 5.
To critically review the methodological quality and synthesize information from systematic reviews and high quality studies on the effects of beta alanine (BA) on exercise and athletic performance.
A search strategy was developed in accordance with the standards for the reporting of scientific literature via systematic reviews. Five databases were thoroughly searched from inception to November 2012. Inclusion criteria were English language, human studies, used BA to increase exercise or athletic performance, systematic reviews or randomized controlled trials and were published in a peer-reviewed journal. Included studies were systematically graded for their methodological quality by rotating pairs of reviewers and the results were qualitatively synthesized.
One systematic review and 19 randomized trials were included in this review. There is one systematic review with several methodological weaknesses that limit the confidence in its results. There are moderate to high quality studies that appear to support that BA may increase power output and working capacity, decrease the feeling of fatigue and exhaustion, and have of positive effect on body composition and carnosine content. The reporting of side effects from BA supplementation in the athletic population was generally under-reported.
There appears to be some evidence from this review that supplementation with BA may increase athletic performance. However, there is insufficient evidence examining the safety of BA supplementation and its side effects. It is therefore recommended to err on the side of caution in using BA as an ergogenic aid until there is sufficient evidence confirming its safety.
严格审查方法学质量，并综合系统评价和高质量研究中有关β-丙氨酸（BA）对运动及运动表现影响的信息。
根据科学文献报告标准，通过系统评价制定检索策略。全面检索了5个数据库，时间跨度从建库至2012年11月。纳入标准为英文文献、人体研究、使用BA来提高运动或运动表现、系统评价或随机对照试验，且发表于同行评审期刊。由评审员两两轮流对纳入研究的方法学质量进行系统评分，并对结果进行定性综合分析。
本评价纳入了1篇系统评价和19项随机试验。有1篇系统评价存在若干方法学弱点，限制了对其结果的可信度。有中等至高质量的研究似乎支持BA可能会增加功率输出和工作能力、减轻疲劳和疲惫感，并对身体成分和肌肽含量有积极影响。在运动员群体中，关于补充BA的副作用报告普遍不足。
本评价似乎有一些证据表明补充BA可能会提高运动表现。然而，审查补充BA的安全性及其副作用的证据不足。因此，在有足够证据证实其安全性之前，建议谨慎使用BA作为一种提高运动能力的辅助手段。
