用于斑秃治疗的308纳米准分子灯：16例临床试验
308-nm Excimer Lamp for the Treatment of Alopecia Areata: Clinical Trial on 16 Cases.
作者信息
Ohtsuki Akiko, Hasegawa Toshio, Komiyama Etsuko, Takagi Atsushi, Kawasaki Junko, Ikeda Shigaku
机构信息
Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan.
出版信息
Indian J Dermatol. 2013 Jul;58(4):326. doi: 10.4103/0019-5154.113954.
Abstract
BACKGROUND
Alopecia areata (AA) is considered as a T-cell mediated autoimmune disorder. The 308-nm excimer laser is thought to be capable of inducing T-cell apoptosis in vitro, suggesting that the 308-nm excimer lamp (not laser) might be effective for the treatment of AA. We examined the effectiveness of the 308-nm excimer lamp for treating AA.
MATERIALS AND METHODS
We treated 16 patients with single AA and multiple AA (MAA). The lesions were irradiated with a 308-nm excimer lamp at 2-week intervals.
RESULTS
Hair regrowth was observed in 14 patients. Among them, 10 patients showed more than 50% hair re-growth. Our results suggested that the 308-nm excimer lamp system is effective and safe for the treatment of single AA and MAA.
CONCLUSION
Our results suggest that the 308-nm excimer lamp is a good therapeutic alternative without serious side effect for treating AA.
摘要
背景
斑秃（AA）被认为是一种T细胞介导的自身免疫性疾病。308纳米准分子激光被认为在体外能够诱导T细胞凋亡，这表明308纳米准分子灯（非激光）可能对斑秃的治疗有效。我们研究了308纳米准分子灯治疗斑秃的有效性。
材料与方法
我们治疗了16例单发斑秃和多发斑秃（MAA）患者。每隔2周用308纳米准分子灯照射皮损。
结果
14例患者出现毛发再生。其中，10例患者毛发再生超过50%。我们的结果表明，308纳米准分子灯系统治疗单发斑秃和多发斑秃有效且安全。
结论
我们的结果表明，308纳米准分子灯是治疗斑秃的一种良好治疗选择，且无严重副作用。
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