Ohtsuki Akiko, Hasegawa Toshio, Komiyama Etsuko, Takagi Atsushi, Kawasaki Junko, Ikeda Shigaku
Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan.
Indian J Dermatol. 2013 Jul;58(4):326. doi: 10.4103/0019-5154.113954.
Alopecia areata (AA) is considered as a T-cell mediated autoimmune disorder. The 308-nm excimer laser is thought to be capable of inducing T-cell apoptosis in vitro, suggesting that the 308-nm excimer lamp (not laser) might be effective for the treatment of AA. We examined the effectiveness of the 308-nm excimer lamp for treating AA.
We treated 16 patients with single AA and multiple AA (MAA). The lesions were irradiated with a 308-nm excimer lamp at 2-week intervals.
Hair regrowth was observed in 14 patients. Among them, 10 patients showed more than 50% hair re-growth. Our results suggested that the 308-nm excimer lamp system is effective and safe for the treatment of single AA and MAA.
Our results suggest that the 308-nm excimer lamp is a good therapeutic alternative without serious side effect for treating AA.
斑秃（AA）被认为是一种T细胞介导的自身免疫性疾病。308纳米准分子激光被认为在体外能够诱导T细胞凋亡，这表明308纳米准分子灯（非激光）可能对斑秃的治疗有效。我们研究了308纳米准分子灯治疗斑秃的有效性。
我们治疗了16例单发斑秃和多发斑秃（MAA）患者。每隔2周用308纳米准分子灯照射皮损。
14例患者出现毛发再生。其中，10例患者毛发再生超过50%。我们的结果表明，308纳米准分子灯系统治疗单发斑秃和多发斑秃有效且安全。
我们的结果表明，308纳米准分子灯是治疗斑秃的一种良好治疗选择，且无严重副作用。
