Nature. 2013 Aug 15;500(7462):283-4. doi: 10.1038/nature12544. Epub 2013 Aug 7.
The phenomenon of catabolite repression enables microorganisms to use their favourite carbon source first. New work reveals α-ketoacids as key effectors of this process, with their levels regulating gene expression.
分解代谢物阻遏现象使微生物能够首先利用它们最喜欢的碳源。新的研究揭示了α-酮酸作为该过程的关键效应物,其水平调节基因表达。