Judy Mohsen, Sodagar Amir M, Lotfi Reza, Sawan Mohamad
IEEE Trans Biomed Circuits Syst. 2014 Jun;8(3):371-81. doi: 10.1109/TBCAS.2013.2270178. Epub 2013 Aug 2.
A nonlinear ADC dedicated to the digitization of neural signals in implantable brain-machine interfaces is presented. Benefitting from an exponential quantization function, effective resolution of the proposed ADC in the digitization of action potentials is almost 2 bits more than its physical number of bits. Hence, it is shown in this paper that the choice of a proper nonlinear quantization function helps reduce the outgoing bit rate carrying the recorded neural data. Another major benefit of digitizing neural signals using the proposed signal-specific ADC is the considerable reduction in the background noise of the neural signal. The 8-b exponential ADC reported in this paper digitizes large action potentials with maximum resolution of 10.5 bits , while quantizing the small background noise is performed with a resolution of as low as 3 bits. Fully-integrated version of the circuit was designed and fabricated in a 0.18-μm CMOS process, occupying 0.036 mm(2) silicon area. Designed based on a two-step successive-approximation register ADC architecture, the proposed ADC employs a piecewise-linear approximation of the target exponential function for quantization. Operating at a sampling frequency of 25 kS/s (typical for intra-cortical neural recording) and with a supply voltage of 1.8 V, the entire chip, including the ADC and reference circuits, dissipates 87.2 μW. According to the experiments, Noise-Content-Reduction Ratio (NCRR) of the ADC is 41.1 dB.
本文介绍了一种用于植入式脑机接口中神经信号数字化的非线性模数转换器(ADC)。得益于指数量化函数,该ADC在动作电位数字化方面的有效分辨率比其物理位数多出近2位。因此,本文表明选择合适的非线性量化函数有助于降低传输记录神经数据的输出比特率。使用所提出的特定信号ADC对神经信号进行数字化的另一个主要好处是神经信号背景噪声的显著降低。本文报道的8位指数ADC以10.5位的最大分辨率对大动作电位进行数字化,而对小背景噪声的量化分辨率低至3位。该电路的全集成版本采用0.18μm CMOS工艺设计和制造,占用0.036平方毫米的硅面积。基于两步逐次逼近寄存器ADC架构设计,所提出的ADC采用目标指数函数的分段线性近似进行量化。在25 kS/s的采样频率(典型的皮层内神经记录频率)下工作,电源电压为1.8 V,整个芯片,包括ADC和参考电路,功耗为87.2μW。根据实验,该ADC的噪声含量降低率(NCRR)为41.1 dB。