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本文引用的文献

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Managing Clinical Knowledge for Health Care Improvement.管理临床知识以改善医疗保健。
Yearb Med Inform. 2000(1):65-70.
2
From an infrastructure to a service-based business model: 5 years of mobile clinical research at the University of Michigan.从基础设施到基于服务的商业模式:密歇根大学五年的移动临床研究
Clin Transl Sci. 2013 Feb;6(1):3-6. doi: 10.1111/cts.12023. Epub 2013 Jan 14.
3
Strategies for a National Evaluation of the Clinical and Translational Science Awards.国家临床与转化科学奖评估策略。
Clin Transl Sci. 2012 Apr;5(2):138-9. doi: 10.1111/j.1752-8062.2011.00381.x. Epub 2012 Feb 23.
4
Practice-based research--"Blue Highways" on the NIH roadmap.基于实践的研究——美国国立卫生研究院路线图上的“蓝色高速公路”。
JAMA. 2007 Jan 24;297(4):403-6. doi: 10.1001/jama.297.4.403.

估算转化研究投资回报率:方法与方案。

Estimating return on investment in translational research: methods and protocols.

机构信息

Michigan Institute for Clinical and Health Research, School of Public Health, School of Medicine, University of Michigan, Ann Arbor, MI, USA.

出版信息

Eval Health Prof. 2013 Dec;36(4):478-91. doi: 10.1177/0163278713499587. Epub 2013 Aug 7.

DOI:10.1177/0163278713499587
PMID:23925706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4084908/
Abstract

Assessing the value of clinical and translational research funding on accelerating the translation of scientific knowledge is a fundamental issue faced by the National Institutes of Health (NIH) and its Clinical and Translational Awards (CTSAs). To address this issue, the authors propose a model for measuring the return on investment (ROI) of one key CTSA program, the clinical research unit (CRU). By estimating the economic and social inputs and outputs of this program, this model produces multiple levels of ROI: investigator, program, and institutional estimates. A methodology, or evaluation protocol, is proposed to assess the value of this CTSA function, with specific objectives, methods, descriptions of the data to be collected, and how data are to be filtered, analyzed, and evaluated. This article provides an approach CTSAs could use to assess the economic and social returns on NIH and institutional investments in these critical activities.

摘要

评估临床和转化研究资金在加速科学知识转化方面的价值,是美国国立卫生研究院(NIH)及其临床和转化奖(CTSAs)面临的一个基本问题。为了解决这个问题,作者提出了一种衡量关键 CTSA 项目之一——临床研究单位(CRU)投资回报率(ROI)的模型。通过估计该计划的经济和社会投入和产出,该模型产生了多个层次的 ROI:研究人员、计划和机构的估计。本文提出了一种方法或评估协议,以评估该 CTSA 功能的价值,包括具体目标、方法、要收集的数据描述以及如何筛选、分析和评估数据。本文为 CTSA 提供了一种评估 NIH 和机构在这些关键活动中投资的经济和社会效益的方法。