年龄、性别和教育程度与 2 型糖尿病的以色列老年患者的认知表现有关。
Age, gender, and education are associated with cognitive performance in an older Israeli sample with type 2 diabetes.
机构信息
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA.
出版信息
Int J Geriatr Psychiatry. 2014 Mar;29(3):299-309. doi: 10.1002/gps.4008. Epub 2013 Aug 8.
Abstract
OBJECTIVE
To evaluate the relationships of age, education, and gender with performance on neuropsychological tests in a cognitively intact, older Israeli sample with type 2 diabetes (T2D).
METHODS
We examined 862 participants, 65-84 years old, enrolled in the Israel Diabetes and Cognitive Decline study. Multiple regression assessed associations of performance on 17 neuropsychological tests, including the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological battery, with age, education, and gender.
RESULTS
Higher education and younger age were consistently associated with better performance. Women outperformed men on all memory tasks; men outperformed women on two non-verbal measures. These patterns of demographic associations with cognitive performance were very similar to those of US cohorts.
CONCLUSIONS
In a cognitively intact, older Israeli sample with T2D, better test performance is associated primarily with higher education, followed by younger age and gender differences. Although T2D is associated with cognitive deficits, it recapitulates the patterns of relationships between cognitive performance and demographic characteristics seen in non-T2D diabetic samples.
摘要
目的
评估年龄、教育程度和性别与认知正常的、患有 2 型糖尿病（T2D）的以色列老年人样本在神经心理学测试中的表现之间的关系。
方法
我们检查了 862 名年龄在 65-84 岁的参与者，他们参加了以色列糖尿病和认知衰退研究。多元回归评估了 17 项神经心理学测试表现与年龄、教育程度和性别的关系，包括阿尔茨海默病协会神经心理学电池登记册。
结果
较高的教育程度和较年轻的年龄与更好的表现始终相关。女性在所有记忆任务上的表现均优于男性；男性在两项非言语测试上的表现优于女性。这些与认知表现相关的人口统计学关联模式与美国队列非常相似。
结论
在认知正常的、患有 T2D 的以色列老年人群体中，更好的测试表现主要与较高的教育程度相关，其次是年龄较小和性别差异。尽管 T2D 与认知缺陷相关，但它再现了在非 T2D 糖尿病样本中观察到的认知表现与人口统计学特征之间的关系模式。
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