Tebeu Pierre Marie, Foumane Pascal, Mbu Robinson, Fosso Gisèle, Biyaga Paul Tjek, Fomulu Joseph Nelson
Department of Obstetrics and Gynaecology, University Hospitals, Yaoundé, Cameroon ; Ligue d'Initiative et de Recherche Active pour la Santé et l'Education de la Femme (LIRASEF), Yaoundé, Cameroon ; Department of Obstetrics and Gynaecology, Regional Hospital, Maroua, Cameroon.
J Reprod Infertil. 2011 Jul;12(3):227-34.
A recent study at the Maroua Provincial Hospital revealed that hypertension in pregnancy was the first cause of maternal death, representing 17.5% of the 63 maternal deaths recorded between 2003 and 2005. Knowing little about the causes, this study was to identify the possible risk factors for hypertensive disorders in pregnancy.
This case-control study was-done at the Maroua Regional Hospital, Cameroon between June 2005 and May 2007. All the 152 deliveries complicated with hypertension were compared and analyzed with 414 pregnancies that were not complicated with the disease. Data analysis was performed using EPI Info 3.5.1. The differences were considered to be significant if the p-values were less than 0.05.
Using univariate analysis, several factors linked to hypertensive disorder in pregnancy were identified. They included early adolescence, nulliparity, illiteracy, lack of occupation and family history of hypertension. At multivariate analysis, the risk of having hypertension during pregnancy remained greater for illiterate women (OR: 1.6; 95%CI: 1.0-2.3), housewives (OR: 2.8; 95%CI: 1.1-6.9), nulliparae (OR: 2.8; 95%CI: 1.5-3.6), women with family histories of hypertension (OR: 3.6; 95%CI: 1.6-8.5) and women with histories of hypertension during pregnancy (OR: 7.0; 95%CI: 3.0-16.4).
Risk factors for hypertensive diseases in pregnancy in Maroua, Cameroon seem to include early teenage status, illiteracy, housewife status, nulliparity and family or personal histories of hypertension. The knowledge about the aforesaid factors seems to lay the tracks for its prevention in Cameroon.
最近在马鲁阿省医院进行的一项研究表明,妊娠期高血压是孕产妇死亡的首要原因,在2003年至2005年记录的63例孕产妇死亡病例中占17.5%。由于对其病因了解甚少,本研究旨在确定妊娠期高血压疾病的可能危险因素。
本病例对照研究于2005年6月至2007年5月在喀麦隆马鲁阿地区医院进行。将152例并发高血压的分娩病例与414例未患该病的妊娠病例进行比较和分析。使用EPI Info 3.5.1进行数据分析。如果p值小于0.05,则认为差异具有统计学意义。
通过单因素分析,确定了几个与妊娠期高血压疾病相关的因素。包括青春期早期、未生育、文盲、无职业以及高血压家族史。在多因素分析中,文盲女性(比值比:1.6;95%置信区间:1.0 - 2.3)、家庭主妇(比值比:2.8;95%置信区间:1.1 - 6.9)、未生育女性(比值比:2.8;95%置信区间:1.5 - 3.6)、有高血压家族史的女性(比值比:3.6;95%置信区间:1.6 - 8.5)以及孕期有高血压病史的女性(比值比:7.0;95%置信区间:3.0 - 16.4)在孕期患高血压的风险仍然更高。
在喀麦隆马鲁阿,妊娠期高血压疾病的危险因素似乎包括青少年早期状态、文盲、家庭主妇身份、未生育以及高血压家族史或个人病史。了解上述因素似乎为喀麦隆预防该病奠定了基础。