Rieder H L, Cauthen G M, Bloch A B, Cole C H, Holtzman D, Snider D E, Bigler W J, Witte J J
Division of Tuberculosis Control, Centers for Disease Control, Atlanta, Ga 30333.
Arch Intern Med. 1989 Jun;149(6):1268-73.
Florida reported 1858 cases of the acquired immunodeficiency syndrome (AIDS) and 8455 cases of tuberculosis from January 1, 1981, through October 31, 1986. Of the patients with AIDS, 159 (8.6%) also had tuberculosis, and 154 (1.8%) of the patients with tuberculosis also had AIDS. Among patients with both diagnoses, tuberculosis was diagnosed before AIDS by more than 1 month in 50%, was diagnosed within 1 month before or 1 month after the diagnosis of AIDS in 30%, and was diagnosed more than 1 month after the AIDS diagnosis in 20%. Compared with patients with AIDS only, patients with both diagnoses were also more likely to be Haitian, black (other than Haitian), or Hispanic. Compared with patients with tuberculosis only, patients with both diagnoses were more likely to be younger, male, Haitian, black (other than Haitian), and Hispanic, have extrapulmonary tuberculosis and negative tuberculin skin tests, and have noncavitary chest roentgenograms. These data suggest that patients with AIDS may have an increased risk of tuberculosis and that patients with both diagnoses differ in important demographic and clinical characteristics from patients with AIDS only or tuberculosis only.
从1981年1月1日至1986年10月31日,佛罗里达州报告了1858例获得性免疫缺陷综合征(艾滋病)病例和8455例结核病病例。在艾滋病患者中,159例(8.6%)同时患有结核病,在结核病患者中,154例(1.8%)同时患有艾滋病。在两种疾病都被诊断出的患者中,50%的患者结核病在艾滋病诊断前1个月以上被诊断出来,30%的患者结核病在艾滋病诊断前1个月内或诊断后1个月内被诊断出来,20%的患者结核病在艾滋病诊断后1个月以上被诊断出来。与仅患有艾滋病的患者相比,两种疾病都被诊断出的患者更有可能是海地人、黑人(非海地人)或西班牙裔。与仅患有结核病的患者相比,两种疾病都被诊断出的患者更有可能年龄更小、为男性、是海地人、黑人(非海地人)和西班牙裔,患有肺外结核且结核菌素皮肤试验呈阴性,胸部X光片无空洞。这些数据表明,艾滋病患者患结核病的风险可能增加,且两种疾病都被诊断出的患者在重要的人口统计学和临床特征方面与仅患有艾滋病或仅患有结核病的患者不同。