Popli S, Leehey D J, Daugirdas J T, Bansal V K, Ho D S, Hano J E, Ing T S
Department of Medicine, Veterans Administration Hospital, Hines, Ill. 60141.
Arch Intern Med. 1990 Sep;150(9):1962-4.
We describe five patients with asymptomatic, nonketotic, severe hyperglycemia (serum glucose concentrations between 45.8 and 92 mmol/L) in the face of renal insufficiency are described. As opposed to most of the previously described patients with hyperglycemic, nonketotic, hyperosmolar coma, our patients were hyponatremic. The lack of symptoms in our patients may be related to the absence of cerebral cellular dehydration. Aggressive treatment of hyperglycemia in such patients is unnecessary. Attention to the serum sodium level as well as to the serum glucose concentration will allow recognition of this clinical entity.
我们描述了5例肾功能不全患者，他们存在无症状、非酮症性的严重高血糖（血清葡萄糖浓度在45.8至92 mmol/L之间）。与大多数先前描述的高血糖、非酮症性高渗性昏迷患者不同，我们的患者存在低钠血症。我们的患者没有症状可能与不存在脑细胞脱水有关。对此类患者积极治疗高血糖并无必要。关注血清钠水平以及血清葡萄糖浓度将有助于识别这一临床实体。
