HIV Prevention Research Unit, Medical Research Council, 123 Jan Hofmeyr Road, Westville, Durban, South Africa,
AIDS Behav. 2014 Feb;18(2):317-22. doi: 10.1007/s10461-013-0578-x.
We investigated geographical variations of three sexually transmitted infections (STIs) namely chlamydia, gonorrhea and syphilis in the greater Durban area, so as to optimize intervention strategies. The study population was a cohort of sexually active women who consented to be screened in one of three biomedical studies conducted in Durban. A total of nine local regions collectively formed three clusters at screening, five of which were previously defined as HIV hot-spots. STI cases were geo-coded at the census level based on residence at the time of screening. Spatial SaTScan Statistics software was employed to identify the areas with a disproportionate prevalence and incidence of STI infection when compared to the neighboring areas under study. Both prevalence and incidence of STIs were collectively clustered in several localized areas, and the majority of these locations overlapped with high HIV clusters and shared the same characteristics: younger age, not married/cohabitating and multiple sex partners.
我们调查了德班大都市区三种性传播感染（STI），即衣原体、淋病和梅毒的地理差异，以便优化干预策略。研究人群为一组同意在德班进行的三项生物医学研究之一中接受筛查的性活跃女性。共有九个地方区域在筛查时共同形成了三个集群，其中五个之前被定义为 HIV 热点。根据筛查时的居住地，将 STI 病例在普查水平上进行地理编码。使用空间 SaTScan 统计软件来识别与研究中的相邻地区相比，STI 感染的流行率和发病率不成比例的地区。STI 的流行率和发病率都集中在几个局部地区，其中大多数地点与 HIV 高发集群重叠，并具有相同的特征：年龄较轻、未婚/同居和多个性伴侣。
