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疼痛状况下的精神疾病发病率:来自新加坡心理健康研究的结果。

Psychiatric morbidity in pain conditions: results from the Singapore Mental Health Study.

机构信息

Research Division, Institute of Mental Health, Buangkok Green Medical Park, Singapore.

出版信息

Pain Res Manag. 2013 Jul-Aug;18(4):185-90. doi: 10.1155/2013/798205.

Abstract

BACKGROUND

Chronic pain is a common problem among the general population and has been found to be associated with psychiatric disorders in studies based on both clinical samples and epidemiological surveys.

OBJECTIVES

To establish the prevalence, correlates and comorbidities of chronic pain disorders among the adult population of Singapore.

METHODS

The data used in the present analysis were derived from the Singapore Mental Health Study, a cross-sectional epidemiological survey of a representative sample of the adult resident population of Singapore. Diagnoses of psychiatric disorders were established using the Composite International Diagnostic Interview version 3.0. A modified version of the Composite International Diagnostic Interview 3.0 checklist of chronic medical disorders was used, in which the chronic medical disorders were reclassified into eight types of physical disorders. Chronic pain disorders included arthritis or rheumatism, back problems including disk or spine problems, and migraine headaches.

RESULTS

The lifetime prevalence estimates for arthritis, back pain and migraine in the Singapore general population were 6.0% (n=282), 7.0% (n=436) and 5.6% (n=446), respectively. After adjusting for sociodemographic factors, comorbid pain disorders and the presence of other chronic physical conditions, migraine remained significantly associated with major depressive disorder (adjusted OR=2.4), generalized anxiety disorder (adjusted OR=3.0) and alcohol use disorders (adjusted OR=2.1), while back pain was significantly associated with major depressive disorder (adjusted OR=2.0).

CONCLUSIONS

The significant association between pain and psychiatric disorders emphasizes the need to screen individuals with chronic pain conditions for psychiatric disorders, particularly depression. There is a need to develop integrated pharmacological and psychological treatments for both conditions.

摘要

背景

慢性疼痛是普通人群中的常见问题,在基于临床样本和流行病学调查的研究中发现,它与精神障碍有关。

目的

确定新加坡成年人群中慢性疼痛障碍的患病率、相关因素和共病情况。

方法

本分析中使用的数据来自新加坡心理健康研究,这是一项对新加坡成年居民代表性样本进行的横断面流行病学调查。使用复合国际诊断访谈第 3.0 版确定精神障碍的诊断。使用复合国际诊断访谈第 3.0 版的慢性医学障碍检查表的修改版本,其中慢性医学障碍重新分类为八种类型的身体障碍。慢性疼痛障碍包括关节炎或风湿病、包括椎间盘或脊柱问题的背部问题以及偏头痛。

结果

新加坡普通人群中关节炎、背痛和偏头痛的终身患病率估计值分别为 6.0%(n=282)、7.0%(n=436)和 5.6%(n=446)。在调整了社会人口因素、共病疼痛障碍和其他慢性身体状况的存在后,偏头痛仍与重度抑郁症(调整后的 OR=2.4)、广泛性焦虑症(调整后的 OR=3.0)和酒精使用障碍(调整后的 OR=2.1)显著相关,而背痛与重度抑郁症(调整后的 OR=2.0)显著相关。

结论

疼痛与精神障碍之间的显著关联强调了需要对患有慢性疼痛疾病的个体进行精神障碍筛查,尤其是抑郁症。需要开发针对这两种疾病的综合药物和心理治疗方法。

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本文引用的文献

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The Singapore Mental Health Study: an overview of the methodology.新加坡精神健康研究:方法学概述。
Int J Methods Psychiatr Res. 2012 Jun;21(2):149-57. doi: 10.1002/mpr.1351. Epub 2012 Feb 13.
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Impact of pain on the course of depressive and anxiety disorders.疼痛对抑郁和焦虑障碍病程的影响。
Pain. 2012 Feb;153(2):429-436. doi: 10.1016/j.pain.2011.11.001. Epub 2011 Dec 10.
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Depressive symptoms in patients with chronic pain.慢性疼痛患者的抑郁症状
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