Villiger Martin, Zhang Ellen Ziyi, Nadkarni Seemantini K, Oh Wang-Yuhl, Vakoc Benjamin J, Bouma Brett E
Wellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.
Opt Express. 2013 Jul 15;21(14):16353-69. doi: 10.1364/OE.21.016353.
Polarization mode dispersion (PMD) has been recognized as a significant barrier to sensitive and reproducible birefringence measurements with fiber-based, polarization-sensitive optical coherence tomography systems. Here, we present a signal processing strategy that reconstructs the local retardation robustly in the presence of system PMD. The algorithm uses a spectral binning approach to limit the detrimental impact of system PMD and benefits from the final averaging of the PMD-corrected retardation vectors of the spectral bins. The algorithm was validated with numerical simulations and experimental measurements of a rubber phantom. When applied to the imaging of human cadaveric coronary arteries, the algorithm was found to yield a substantial improvement in the reconstructed birefringence maps.
偏振模色散（PMD）已被公认为是基于光纤的偏振敏感光学相干断层扫描系统进行灵敏且可重复的双折射测量的重大障碍。在此，我们提出一种信号处理策略，该策略能在存在系统PMD的情况下稳健地重建局部延迟。该算法采用光谱分箱方法来限制系统PMD的有害影响，并受益于光谱分箱的PMD校正延迟矢量的最终平均。该算法通过数值模拟和橡胶模型的实验测量得到了验证。当应用于人体尸体冠状动脉成像时，发现该算法在重建的双折射图方面有显著改善。
