振动疗法治疗帕金森病：重新审视 Charcot 的研究。

Vibration therapy for Parkinson's disease: Charcot's studies revisited.

机构信息

Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.

出版信息

J Parkinsons Dis. 2012;2(1):23-7. doi: 10.3233/JPD-2012-12079.

DOI:10.3233/JPD-2012-12079

Abstract

The 19th century neurologist, J-M Charcot, used a vibration chair for treating Parkinson's disease (PD). He documented improvement, but few subsequent studies examined vibration treatment. Using a specialized lounge chair, we conducted a rater blinded, randomized trial of body vibration vs. no vibration in 23 PD patients. The primary outcome measure was change from baseline in the motor section of the MDS-UPDRS. Both vibration and no vibration groups significantly improved after one month of daily treatments. However, there was no significant difference between the two treatment groups, suggesting that non-specific or placebo factors had an effect on PD motor function.

摘要

19 世纪的神经病学家 J-M·沙可（J-M Charcot）曾使用振动椅治疗帕金森病（PD）。他记录到了改善，但很少有后续研究检查过振动治疗。我们使用专门的躺椅，在 23 名 PD 患者中进行了一项盲法、随机试验，比较了身体振动与无振动治疗。主要结局测量指标是 MDS-UPDRS 运动部分的基线变化。振动组和无振动组在一个月的每日治疗后均显著改善。然而，两组之间没有显著差异，这表明非特异性或安慰剂因素对 PD 运动功能有影响。