Moradi Saeed, Bidar Maryam, Zarrabi Mohammad Hasan, Talati Ali
Department of Endodontics, Dental School, Dental Research Center, Mashad University of Medical Sciences, Mashad, Iran.
Iran Endod J. 2009 Spring;4(2):49-52. Epub 2009 Apr 17.
Open-apex teeth with irreversible pulpitis require complex and difficult treatment. Providing the right environment for apexogenesis and pulp protection is vital for their long term prognosis. The young pulp of open apex tooth, however, is better equipped against irritation and assault. The aim of this study was to evaluate pulp inflammation in open apex canine teeth of cats.
In this in vivo study, twelve cats with open apex canines were used. Pulps were iatrogenically exposed and the animals were sacrificed at one, seven, thirty and ninety days after pulp exposure. Samples were prepared for histological evaluations.
During the first and seventh day, changes were limited to acute inflammation in the coronal pulp. During the first month pulp changes in 45.5% of samples were similar to the seventh day. In the other samples necrosis and abscess spread to the end of the root, and internal resorption and periapical abscess were observed. In 45.5% of samples in the apical region vital tissue was barely observed (during 90 days); in 54.5% of samples however, complete pulp necrosis, internal resorption and a large periapical lesion was observed.
In one and seven-day periods pulp tissue was vital, however, in the thirty and ninety-day periods, minority of the pulp samples were vital.
患有不可逆性牙髓炎的开放根尖牙齿需要复杂且困难的治疗。为根尖形成和牙髓保护提供合适的环境对其长期预后至关重要。然而，开放根尖牙齿的年轻牙髓对刺激和攻击具有更好的抵抗力。本研究的目的是评估猫开放根尖犬齿的牙髓炎症。
在这项体内研究中，使用了12只开放根尖犬齿的猫。牙髓被医源性暴露，动物在牙髓暴露后1天、7天、30天和90天处死。制备样本用于组织学评估。
在第1天和第7天，变化仅限于冠部牙髓的急性炎症。在第1个月，45.5%的样本牙髓变化与第7天相似。在其他样本中，坏死和脓肿扩散到根尖，观察到内部吸收和根尖周脓肿。在90天期间，45.5%的根尖区域样本中几乎未观察到有活力的组织；然而，在54.5%的样本中，观察到完全牙髓坏死、内部吸收和大的根尖周病变。
在1天和7天期间，牙髓组织是有活力的，然而，在30天和90天期间，少数牙髓样本是有活力的。
