Smajlović Dzevdet, Salihović Denisa, Ibrahimagić Omer C, Sinanović Osman
University of Tuzla, Tuzla University Clinical Centre, Medical Faculty, Department of Neurology, Tuzla, Bosnia and Herzegovina.
Coll Antropol. 2013 Jun;37(2):515-9.
The aim of the study was to analyze stroke in young adults in Tuzla Canton, Bosnia and Herzegovina. From January 2001 to December 2005, 3864 patients with first-ever stroke were admitted at the Department of Neurology Tuzla. A retrospective analysis of risk factors, stroke types, severity and one month outcome in all young adults (18-45 years of age) with first-ever stroke was carried out. Out of total, there were 154 (4%) young adults with stroke. Mean age was 38.8 +/- 5.7 years and 47% were women. The leading risk factors were smoking (56%) and hypertension (45%). Subarachnoid hemorrhage (SAH) was more frequent in young adults compared with older patients (> 45 years of age) (22% vs. 3.5%, p < 0.0001), intracerebral hemorrhage (ICH) was similar in both groups (16.9% vs. 15.8%, p = 0.7), but ischemic stroke (IS) was predominant stroke type in the older group (61% vs. 74%, p = 0.0004). Young adults had more frequent lacunar stroke (26.6% vs. 16.1%, p = 0.01) and stroke due to other etiology (8.5% vs. 1.8%, p = 0.0004) than stroke patients over 45 years of age. Stroke severity at admission was lower in young adults than in older patients (p < 0.0001), as well as mortality at one month (11% vs. 30%, p < 0.0001). Favorable outcome (modified Rankin Scale < or = 2) had 71% of young adults compared with only 53% of patients in the older group (p = 0.0003). Stroke in young adults in Tuzla Canton is rare. Risk factors profile, stroke types, severity and outcome at one month in young adults are different from those in older patients.
该研究的目的是分析波斯尼亚和黑塞哥维那图兹拉州年轻成年人的中风情况。2001年1月至2005年12月期间，图兹拉神经病学系收治了3864例首次中风患者。对所有首次中风的年轻成年人（18至45岁）的危险因素、中风类型、严重程度及1个月的预后进行了回顾性分析。总共有154名（4%）年轻成年人患有中风。平均年龄为38.8±5.7岁，47%为女性。主要危险因素为吸烟（56%）和高血压（45%）。与老年患者（>45岁）相比，年轻成年人蛛网膜下腔出血（SAH）更为常见（22%对3.5%，p<0.0001），两组脑内出血（ICH）相似（16.9%对15.8%，p = 0.7），但缺血性中风（IS）在老年组中是主要的中风类型（61%对74%，p = 0.0004）。与45岁以上的中风患者相比，年轻成年人腔隙性中风（26.6%对16.1%，p = 0.01）和其他病因导致的中风（8.5%对1.8%，p = 0.0004）更为常见。年轻成年人入院时的中风严重程度低于老年患者（p<0.0001），1个月时的死亡率也是如此（11%对30%，p<0.0001）。71%的年轻成年人预后良好（改良Rankin量表≤2），而老年组患者中这一比例仅为53%（p = 0.0003）。图兹拉州年轻成年人中风较为罕见。年轻成年人的危险因素、中风类型、严重程度及1个月的预后与老年患者不同。
