Broering Jeanette M, Paciorek Alan, Carroll Peter R, Wilson Leslie S, Litwin Mark S, Miaskowski Christine
Department of Urology, UCSF Helen Diller Family Comprehensive Cancer Center, School of Medicine, University of California San Francisco (UCSF), 3333 California Street, Suite 282, San Francisco, CA, 94143-1355, USA,
Qual Life Res. 2014 Mar;23(2):495-508. doi: 10.1007/s11136-013-0493-7. Epub 2013 Aug 13.
To evaluate the effects of mode, order of administration, and the interaction of mode and order on health-related quality of life scales when self-administered by mixed mode (paper-mode and web-mode) for measurement equivalence.
Health-related quality of life data was analyzed from the Cancer of the Prostate Strategic Urologic Research Endeavor using the Medical Outcomes Study (MOS) Short Form-36 (SF-36) and the University of California Los Angeles Prostate Cancer Index (UCLA-PCI). A randomized crossover design assigned participants to two groups with a preferred 2-5-day washout period. Cognitive debriefing evaluated participants' mode preference.
Of the 245 men enrolled, 85 % completed both modes. The majority were White (97 %), college educated (66 %), reported an annual income >$75,000 (46 %), and a median age of 69 years. Intraclass correlation coefficients were high for each item on both instruments (r = .54-.97). Exact percentage agreement for yes/no items was high (≥.88). For the SF-36, significant differences were observed for order of administration (physical component and physical function scores) and for the interaction between mode and order (mental component, role emotional, social function, vitality, and mental health scores). For the UCLA-PCI, the largest difference was 12.8 points lower for sexual bother for order of administration by web-mode first (p = .03). Seventy percent preferred the web-mode, 21 % had no preference, and 9 % preferred the paper-mode.
Web-mode and paper-mode administrations of the SF-36 and UCLA-PCI are equivalent in men with prostate cancer, implying that mixed-mode survey administration is warranted.
评估在通过混合模式（纸质模式和网络模式）进行自我管理以实现测量等效性时，模式、给药顺序以及模式与顺序的相互作用对健康相关生活质量量表的影响。
使用医学结局研究（MOS）简表36（SF - 36）和加利福尼亚大学洛杉矶分校前列腺癌指数（UCLA - PCI），对前列腺癌战略泌尿学研究计划中的健康相关生活质量数据进行分析。采用随机交叉设计，将参与者分为两组，设置2 - 5天的洗脱期。认知汇报评估参与者的模式偏好。
在245名登记的男性中，85%完成了两种模式。大多数为白人（97%），接受过大学教育（66%），报告年收入超过75,000美元（46%），中位年龄为69岁。两种工具上每个项目的组内相关系数都很高（r = 0.54 - 0.97）。是/否项目的精确百分比一致性很高（≥0.88）。对于SF - 36，在给药顺序（身体成分和身体功能得分）以及模式与顺序的相互作用（心理成分、角色情感、社会功能、活力和心理健康得分）方面观察到显著差异。对于UCLA - PCI，网络模式先给药时，性困扰方面的最大差异低12.8分（p = 0.03）。70%的人更喜欢网络模式，21%的人无偏好，9%的人更喜欢纸质模式。
SF - 36和UCLA - PCI的网络模式和纸质模式管理在前列腺癌男性中是等效的，这意味着混合模式调查管理是可行的。
