Gao Jun-Feng, Ding Ling, Zhang Peng, Liu Jian-Xun
Research Center of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Zhongguo Zhong Yao Za Zhi. 2013 May;38(10):1556-9.
Chemical constituents were investigated on the ethyl acetate extract of Salvia chinensis. Compounds were separated and purified by various chromatograhic techniques including silica gel, Sephadex LH-20 and reversed-phase HPLC. Their structures were identified by spectroscopic data analysis. Eleven compounds were isolated and purified and their structures were identified as oresbiusin A(1), ethyl dihydrocaffeate (2), ethyl rosmarinate (3), rosmarinic acid (4), methyl rosmarinate (5), bis (2-ethylhexyl) phthalate (6), salvianol acid C (7), methyl salvianol acid C (8), methyl salvianolate A (9), dimethyl lithospermate B (10), and salvianolic acid A(11). Except for rosmarinic acid, the remaining compounds were isolated from S. chinensis for the first time.
对中华鼠尾草的乙酸乙酯提取物中的化学成分进行了研究。通过硅胶、葡聚糖凝胶LH - 20和反相高效液相色谱等多种色谱技术对化合物进行分离和纯化。通过光谱数据分析确定其结构。分离并纯化出11种化合物，其结构被鉴定为奥氏鼠尾草素A（1）、二氢咖啡酸乙酯（2）、迷迭香酸乙酯（3）、迷迭香酸（4）、迷迭香酸甲酯（5）、邻苯二甲酸二（2 - 乙基己基）酯（6）、丹酚酸C（7）、丹酚酸C甲酯（8）、丹酚酸A甲酯（9）、二甲基紫草素B（10）和丹酚酸A（11）。除迷迭香酸外，其余化合物均首次从中华鼠尾草中分离得到。
