Oguri Tomoko, Yoshinaga Jun, Tao Hiroaki, Nakazato Tetsuya
Department of Environmental Studies, The University of Tokyo, Kashiwa, Chiba, 277-8563, Japan.
Arch Environ Contam Toxicol. 2014 Jan;66(1):100-12. doi: 10.1007/s00244-013-9947-8. Epub 2013 Aug 15.
The concentrations of arsenic (As) species in 19 food composites prepared from 159 food items purchased in Shizuoka city, Japan, were determined (1) to estimate total daily intake of inorganic As (InAs) and some organic As species and (2) to determine food contributing to total daily InAs intake. As analysis included extraction of As species with a synthetic gastric juice (0.07 mol/L HCl + 0.01 % pepsin) from food composite and high-performance liquid chromatography-high efficiency photo-oxidation-hydride generation-inductively coupled plasma mass spectrometry. InAs was detected in 9 of 19 food composites at a concentration of 0.423-450 ng As/g fresh-weight. Daily intake of InAs from cereals was greatest (13 μg/person/day) followed by algae (5.7 μg/person/day), and the intake from the two categories constituted 90 % of the total daily InAs intake of adults (21 μg/person/day on a bioaccessible-fraction basis and 24 μg/person/day on a content basis). Analysis of individual food items showed that rice and hijiki contributed virtually 100 % of InAs from cereals and algae, respectively. The present survey indicated that InAs from rice and hijiki consumption contributed to total daily InAs intake and consequently to significant cancer risk of the general Japanese population. Daily intake of some organic forms of As and their contributing food categories was also estimated.
测定了从日本静冈市购买的159种食品制成的19种食品组合中砷（As）物种的浓度，目的如下：（1）估计无机砷（InAs）和某些有机砷物种的每日总摄入量；（2）确定对每日InAs总摄入量有贡献的食品。砷分析包括用合成胃液（0.07 mol/L HCl + 0.01%胃蛋白酶）从食品组合中提取砷物种，以及高效液相色谱 - 高效光氧化 - 氢化物发生 - 电感耦合等离子体质谱法。在19种食品组合中的9种中检测到InAs，浓度为0.423 - 450 ng As/g鲜重。谷物中InAs的每日摄入量最大（13 μg/人/天），其次是藻类（5.7 μg/人/天），这两类食品的摄入量占成年人每日InAs总摄入量的90%（基于生物可利用分数为21 μg/人/天，基于含量为24 μg/人/天）。对单个食品的分析表明，大米和裙带菜分别几乎占谷物和藻类中InAs的100%。本次调查表明，食用大米和裙带菜中的InAs对每日InAs总摄入量有贡献，因此对日本普通人群的癌症风险有显著影响。还估计了某些有机砷形式的每日摄入量及其贡献的食品类别。
