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Role of the nervous system in the control of proteostasis during innate immune activation: insights from C. elegans.

作者信息

Aballay Alejandro

机构信息

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA.

出版信息

PLoS Pathog. 2013;9(8):e1003433. doi: 10.1371/journal.ppat.1003433. Epub 2013 Aug 8.

DOI:10.1371/journal.ppat.1003433
PMID:23950707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3738498/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0579/3738498/7e6e2dde64cf/ppat.1003433.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0579/3738498/7e6e2dde64cf/ppat.1003433.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0579/3738498/7e6e2dde64cf/ppat.1003433.g001.jpg

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Organismal regulation of XBP-1-mediated unfolded protein response during development and immune activation.机体对 XBP-1 介导的未折叠蛋白反应在发育和免疫激活中的调控。
EMBO Rep. 2012 Sep;13(9):855-60. doi: 10.1038/embor.2012.100. Epub 2012 Jul 13.
3
Physiological IRE-1-XBP-1 and PEK-1 signaling in Caenorhabditis elegans larval development and immunity.
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Bacillus simplex treatment promotes soybean defence against soybean cyst nematodes: A metabolomics study using GC-MS.简单芽孢杆菌处理促进大豆对大豆胞囊线虫的防御：使用 GC-MS 的代谢组学研究。
PLoS One. 2020 Aug 6;15(8):e0237194. doi: 10.1371/journal.pone.0237194. eCollection 2020.
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Molecular Drivers of Lymphocyte Organization in Vertebrate Mucosal Surfaces: Revisiting the TNF Superfamily Hypothesis.脊椎动物黏膜表面淋巴细胞组织的分子驱动因素：重新审视 TNF 超家族假说。
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