Centre for Health Services and Nursing Research, KU Leuven Department of Public Health and Primary Care, Kapucijnenvoer 35, Box 7001, 3000, Leuven, Belgium.
Curr Cardiol Rep. 2013 Oct;15(10):407. doi: 10.1007/s11886-013-0407-x.
Quality of life (QOL) is a key outcome in patients with congenital heart disease (CHD) because CHD has become a chronic condition accompanied by lifelong impairments. Recently, published studies on QOL in adults with CHD have reported inconsistent findings. Patients' QOL seems to depend on multiple factors and is not solely determined by their heart defect and various medical or demographic characteristics. For instance, evidence suggests that a strong sense of coherence might be an important pathway to improve QOL. However, studies on QOL and its determinants are characterized by important methodological differences and limitations, making it impossible to draw firm conclusions. To fill the gaps in the current evidence base, longitudinal and international research is needed. Furthermore, the research field on QOL in CHD should move on from observational studies to interventional research to guide health professionals in improving QOL.
生活质量（QOL）是先天性心脏病（CHD）患者的一个关键结果，因为 CHD 已经成为一种伴随终身损害的慢性疾病。最近，关于成人 CHD 患者生活质量的已发表研究报告结果不一致。患者的生活质量似乎取决于多种因素，而不仅仅取决于他们的心脏缺陷和各种医疗或人口统计学特征。例如，有证据表明，强烈的一致性感可能是改善生活质量的重要途径。然而，生活质量及其决定因素的研究存在重要的方法学差异和局限性，使得不可能得出确凿的结论。为了填补当前证据基础中的空白，需要进行纵向和国际研究。此外，CHD 生活质量研究领域应该从观察性研究转向干预性研究，以指导卫生专业人员改善生活质量。
