Paradowska D, Tomaszewski K A, Bałajewicz-Nowak M, Bereza K, Tomaszewska I M, Paradowski J, Pityński K, Skotnicki P, Greimel E R, Bottomley A
Department of Clinical Oncology, Center of Oncology - Maria Skłodowska-Curie Memorial Institute, Krakow.
Eur J Cancer Care (Engl). 2014 Mar;23(2):214-20. doi: 10.1111/ecc.12103. Epub 2013 Aug 19.
The aim of our study was to undertake a prospective validation study of the Polish version of the EORTC cervical cancer (EORTC QLQ-CX24) module used alongside the EORTC core measure. The translated module was pilot-tested according to the established EORTC guidelines. Patients with histological confirmation of cervical cancer were eligible for the study. All patients filled out the Polish version of the EORTC QLQ-CX24 module in addition to EORTC QLQ-C30 and a demographic questionnaire. Standardised validity and reliability analyses were performed. One hundred and seventy-one patients were enrolled into the study, mean age ± SD: 52.1 ± 9.6. Cronbach alpha coefficients, range 0.81-0.88, showed positive internal consistency. Re-test was undertaken with 40 patients (23.4%). Interclass correlations for the EORTC QLQ-CX24 ranged from 0.85 to 0.89 and proved appropriate test-retest reliability. Satisfactory convergent and discriminant validity in multi-trait scaling analyses was seen. Concluding, the Polish version of the EORTC QLQ-CX24 module is a reliable and valid tool for measuring HRQoL in patients with cervical cancer. It can be fully recommended for use in clinical and epidemiological settings in the Polish population.
我们研究的目的是对与欧洲癌症研究与治疗组织（EORTC）核心测评一起使用的波兰语版EORTC宫颈癌（EORTC QLQ-CX24）模块进行前瞻性验证研究。翻译后的模块根据既定的EORTC指南进行了预测试。经组织学确诊为宫颈癌的患者符合研究条件。所有患者除填写EORTC QLQ-C30和一份人口统计学问卷外，还填写了波兰语版的EORTC QLQ-CX24模块。进行了标准化的效度和信度分析。171名患者纳入研究，平均年龄±标准差：52.1±9.6。克朗巴哈α系数范围为0.81 - 0.88，显示出良好的内部一致性。对40名患者（23.4%）进行了重测。EORTC QLQ-CX24的组内相关性在0.85至0.89之间，证明具有适当的重测信度。在多特质量表分析中观察到了令人满意的收敛效度和区分效度。总之，波兰语版的EORTC QLQ-CX24模块是测量宫颈癌患者健康相关生活质量的可靠且有效的工具。完全推荐在波兰人群的临床和流行病学环境中使用。
