Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.
Saudi Pharm J. 2009 Oct;17(4):295-8. doi: 10.1016/j.jsps.2009.10.006. Epub 2009 Nov 10.
Chemical investigation of the sponge Leucetta chagosensis, has led to the isolation of two new imidazole alkaloids, methyldorimidazole (1), preclathridine B (2) along with the known compounds naamine E (3) and leucettamine C (4). The structures of the newly compounds (1 and 2) were elucidated by employing spectroscopic techniques ((1)H NMR, MS and UV). The structures of the known compounds 3 and 4 were determined by comparison of their (1)H NMR and Mass spectroscopic data with published values.
从海绵 Leucetta chagosensis 中进行的化学成分研究，分离得到了两种新的咪唑生物碱：甲基多利咪唑（1）和前克拉定碱 B（2），以及已知化合物 naamine E（3）和 leucettamine C（4）。新化合物（1 和 2）的结构通过光谱技术（1H NMR、MS 和 UV）进行了阐明。已知化合物 3 和 4 的结构通过与已发表的值比较其 1H NMR 和质谱数据来确定。
