从 chagosensis 海绵中分离得到的两种新咪唑生物碱。
Two new imidazole alkaloids from Leucetta chagosensis sponge.
机构信息
Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.
出版信息
Saudi Pharm J. 2009 Oct;17(4):295-8. doi: 10.1016/j.jsps.2009.10.006. Epub 2009 Nov 10.
Abstract
Chemical investigation of the sponge Leucetta chagosensis, has led to the isolation of two new imidazole alkaloids, methyldorimidazole (1), preclathridine B (2) along with the known compounds naamine E (3) and leucettamine C (4). The structures of the newly compounds (1 and 2) were elucidated by employing spectroscopic techniques ((1)H NMR, MS and UV). The structures of the known compounds 3 and 4 were determined by comparison of their (1)H NMR and Mass spectroscopic data with published values.
摘要
从海绵 Leucetta chagosensis 中进行的化学成分研究，分离得到了两种新的咪唑生物碱：甲基多利咪唑（1）和前克拉定碱 B（2），以及已知化合物 naamine E（3）和 leucettamine C（4）。新化合物（1 和 2）的结构通过光谱技术（1H NMR、MS 和 UV）进行了阐明。已知化合物 3 和 4 的结构通过与已发表的值比较其 1H NMR 和质谱数据来确定。
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