Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Saudi Pharm J. 2011 Apr;19(2):65-74. doi: 10.1016/j.jsps.2011.01.007. Epub 2011 Jan 18.
Chromatographic fractionation of the alcoholic extract of the dried fronds of Adiantum capillus-veneris L. (Adiantaceae) yielded seven compounds: four triterpenoidal compounds belonging to adiantane and filicane groups were isolated from the hexane fraction and identified as isoadiantone (1); isoadiantol-B (2); 3-methoxy-4-hydroxyfilicane (3) and 3,4-dihydroxyfilicane (4) and three flavonoids were isolated from the ethyl acetate fraction and identified as: quercetin (5), quercetin-3-O-glucoside (6) and quercetin-3-O-rutinoside (rutin) (7). The identification of the isolated compounds has been established through their physical, chemical and spectroscopic methods including IR, (1)H NMR, (13)C NMR, HSQC, HMBC, NOESY and MS. Biological studies of the total alcoholic extract, hexane fraction and some of the isolated compounds showed an anti-inflammatory activity while the hypoglycemic study of the total alcoholic extract showed a significant activity.
从凤尾蕨（凤尾蕨科）干燥叶片的醇提物中进行色谱分离，得到了七种化合物：从正己烷部分分离得到的四个三萜类化合物属于 adiantane 和 filicane 组，分别鉴定为 isoadiantone（1）；isoadiantol-B（2）；3-甲氧基-4-羟基 filicane（3）和 3,4-二羟基 filicane（4），从乙酸乙酯部分分离得到的三个黄酮类化合物分别鉴定为：槲皮素（5），槲皮素-3-O-葡萄糖苷（6）和槲皮素-3-O-芸香糖苷（芦丁）（7）。通过物理、化学和光谱方法（包括 IR、（1）H NMR、（13）C NMR、HSQC、HMBC、NOESY 和 MS）确定了分离化合物的结构。总醇提物、正己烷部分和部分分离化合物的生物学研究显示出抗炎活性，而总醇提物的降血糖研究显示出显著的活性。
