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以椎间盘作为青光眼的治疗基础。 (不过从医学常理看,该表述可能不太准确,正常青光眼治疗一般不会以椎间盘为基础,这里可能存在原文表述不太符合常见医学逻辑的情况 )

The disc as the basis of treatment for glaucoma.

作者信息

Zangalli Camila, Gupta Shelly R, Spaeth George L

机构信息

Wills Eye Institute, 840 Walnut Street, Suite 1110, Philadelphia, PA 19107, USA.

出版信息

Saudi J Ophthalmol. 2011 Oct;25(4):381-7. doi: 10.1016/j.sjopt.2011.07.003. Epub 2011 Jul 30.

Abstract

The goal of the treatment of patients with glaucoma is to prevent disability or, if disability already exists, to repair the disability or at the least to prevent further disability from developing. To achieve these goals requires knowing what will happen if there is no treatment and what will happen if there is treatment. That is, one must know the possible benefits from the therapy in comparison to the damage caused by the therapy. As we will demonstrate, the classic risk factors do not provide accurate estimates of the development of disability and do not answer these two questions. The most helpful clues are provided by what the patient says, by whether the disc is damaged and by whether the disc is deteriorating. The severity of disease is best estimated by the nature of the optic disc and how it changes. This report is primarily focused on increasing the skill of the physician in being able to estimate the nature of the optic disc and how that changes. This does not, however, lessen the tremendous importance of careful history-taking and of gonioscopy. In this report, however, we focus on the evaluation of the disc. Currently disc evaluation is often not adequate because of poor examination techniques, reliance on cup/disc ratios, and reliance on the results of image analyzers. We will present here the Disc Damage Likelihood Scale, which is a user-friendly method which correlates accurately with visual field changes.

摘要

青光眼患者的治疗目标是预防残疾,如果残疾已经存在,则修复残疾,或者至少防止残疾进一步发展。要实现这些目标,需要了解不治疗会发生什么以及治疗会发生什么。也就是说,必须知道与治疗造成的损害相比,治疗可能带来的益处。正如我们将证明的,经典的风险因素并不能准确估计残疾的发展,也无法回答这两个问题。最有用的线索来自患者的诉说、视盘是否受损以及视盘是否在恶化。疾病的严重程度最好通过视盘的性质及其变化来估计。本报告主要关注提高医生评估视盘性质及其变化的能力。然而,这并没有降低仔细询问病史和进行前房角镜检查的重要性。在本报告中,我们重点关注视盘评估。目前,由于检查技术不佳、依赖杯盘比以及依赖图像分析仪的结果,对视盘的评估往往不够充分。我们将在此介绍视盘损害可能性量表,这是一种用户友好的方法,与视野变化准确相关。

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本文引用的文献

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[Intraocular pressure in normal human eyes].[正常人类眼睛的眼压]
Klin Monbl Augenheilkd Augenarztl Fortbild. 1958;133(5):662-70.
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Infrequent confirmation of visual field progression.视野进展的确认不常见。
Ophthalmology. 2002 Jun;109(6):1059-65. doi: 10.1016/s0161-6420(02)01043-6.
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The probability of blindness from open-angle glaucoma.开角型青光眼致盲的概率。
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