轻度线粒体解偶联可预防人皮肤成纤维细胞过早衰老。 - Suppr

Suppr

超能文献

Mild mitochondrial uncoupling prevents premature senescence in human dermal fibroblasts.

作者信息

Cho Si Young, Seo Dae-Bang, Kim Wan Gi, Lee Sang-Jun

机构信息

Health Science Research Institute, R&D Center, AmorePacific Corporation, Gyeonggi-do, Korea.

出版信息

J Invest Dermatol. 2014 Feb;134(2):540-543. doi: 10.1038/jid.2013.352. Epub 2013 Aug 20.

DOI:10.1038/jid.2013.352

PMID:23962811

Abstract

摘要

相似文献

Mild mitochondrial uncoupling prevents premature senescence in human dermal fibroblasts.轻度线粒体解偶联可预防人皮肤成纤维细胞过早衰老。

J Invest Dermatol. 2014 Feb;134(2):540-543. doi: 10.1038/jid.2013.352. Epub 2013 Aug 20.

Partial uncoupling of oxidative phosphorylation induces premature senescence in human fibroblasts and yeast mother cells.氧化磷酸化的部分解偶联会诱导人类成纤维细胞和酵母母细胞过早衰老。

Free Radic Biol Med. 2007 Sep 15;43(6):947-58. doi: 10.1016/j.freeradbiomed.2007.06.005. Epub 2007 Jun 13.

Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts.抑制 3-磷酸肌醇依赖性蛋白激酶 1（PDK1）可以逆转人真皮成纤维细胞的细胞衰老。

Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31535-31546. doi: 10.1073/pnas.1920338117. Epub 2020 Nov 23.

Skin Aging, Cellular Senescence and Natural Polyphenols.皮肤衰老、细胞衰老与天然多酚

Int J Mol Sci. 2021 Nov 23;22(23):12641. doi: 10.3390/ijms222312641.

Antioxidants reduce the heterogeneity of the intracellular glutathione level in senescent cell population of human dermal fibroblasts.抗氧化剂可降低人皮肤成纤维细胞衰老细胞群体中细胞内谷胱甘肽水平的异质性。

J Dermatol Sci. 2020 Jun;98(3):195-198. doi: 10.1016/j.jdermsci.2020.04.003. Epub 2020 Apr 24.

Penetrating cations enhance uncoupling activity of anionic protonophores in mitochondria.穿透阳离子增强了阴离子质子载体在线粒体中的解偶联活性。

PLoS One. 2013 Apr 23;8(4):e61902. doi: 10.1371/journal.pone.0061902. Print 2013.

Platycodin D Protects Human Fibroblast Cells from Premature Senescence Induced by H2O2 through Improving Mitochondrial Biogenesis.远志酮 D 通过改善线粒体生物发生来保护人成纤维细胞免受 H2O2 诱导的衰老。

Pharmacology. 2020;105(9-10):598-608. doi: 10.1159/000505593. Epub 2020 Jan 31.

Kinetin delays the onset of ageing characteristics in human fibroblasts.激动素可延缓人类成纤维细胞衰老特征的出现。

Biochem Biophys Res Commun. 1994 Jun 15;201(2):665-72. doi: 10.1006/bbrc.1994.1752.

Creatine and Nicotinamide Prevent Oxidant-Induced Senescence in Human Fibroblasts.肌酸和烟酰胺可预防人成纤维细胞氧化诱导的衰老。

Nutrients. 2021 Nov 16;13(11):4102. doi: 10.3390/nu13114102.

Environmentally-Induced (Extrinsic) Skin Aging: Exposomal Factors and Underlying Mechanisms.环境诱导（外源性）皮肤衰老：外泌体因素和潜在机制。

J Invest Dermatol. 2021 Apr;141(4S):1096-1103. doi: 10.1016/j.jid.2020.12.011. Epub 2021 Feb 1.

引用本文的文献

Cellular energetics and mitochondrial uncoupling in canine aging.犬衰老过程中的细胞能量学和线粒体解偶联。

Geroscience. 2019 Apr;41(2):229-242. doi: 10.1007/s11357-019-00062-6. Epub 2019 Apr 1.

Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox Signaling.线粒体解偶联蛋白：细胞氧化还原信号的微妙调节剂。

Antioxid Redox Signal. 2018 Sep 1;29(7):667-714. doi: 10.1089/ars.2017.7225. Epub 2018 Mar 14.

Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.香烟烟雾暴露对器官型支气管上皮组织培养物的影响评估：含成纤维细胞的单培养和共培养模型的比较

Toxicol Sci. 2015 Sep;147(1):207-21. doi: 10.1093/toxsci/kfv122. Epub 2015 Jun 16.

本文引用的文献

Cysteine-rich protein 61 (CCN1) mediates replicative senescence-associated aberrant collagen homeostasis in human skin fibroblasts.富含半胱氨酸的蛋白 61（CCN1）介导人皮肤成纤维细胞复制性衰老相关的异常胶原稳态失衡。

J Cell Biochem. 2012 Sep;113(9):3011-8. doi: 10.1002/jcb.24179.

Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes.AMP 激活的蛋白激酶的急性激活可预防人原代角质细胞中 H2O2 诱导的过早衰老。

PLoS One. 2012;7(4):e35092. doi: 10.1371/journal.pone.0035092. Epub 2012 Apr 13.

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin.由Sod2缺乏引起的线粒体氧化应激会促进皮肤中的细胞衰老和衰老表型。

Aging (Albany NY). 2012 Jan;4(1):3-12. doi: 10.18632/aging.100423.

Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation.线粒体 c-Jun N-末端激酶（JNK）信号启动生理变化，导致活性氧生成的放大。

J Biol Chem. 2011 May 6;286(18):16052-62. doi: 10.1074/jbc.M111.223602. Epub 2011 Mar 16.

Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase.活性氧通过 c-Jun-N-末端激酶控制衰老相关的基质金属蛋白酶-1。

J Cell Physiol. 2010 Oct;225(1):52-62. doi: 10.1002/jcp.22193.

Role of antioxidants in the skin: anti-aging effects.抗氧化剂在皮肤中的作用：抗衰老作用。

J Dermatol Sci. 2010 May;58(2):85-90. doi: 10.1016/j.jdermsci.2010.03.003. Epub 2010 Mar 17.

C. elegans longevity pathways converge to decrease mitochondrial membrane potential.秀丽隐杆线虫的长寿途径会共同作用以降低线粒体膜电位。

Mech Ageing Dev. 2009 Jul;130(7):461-5. doi: 10.1016/j.mad.2009.05.001. Epub 2009 May 12.

Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin.胶原蛋白片段化会促进氧化应激，并提高老年人皮肤成纤维细胞中的基质金属蛋白酶-1水平。

Am J Pathol. 2009 Jan;174(1):101-14. doi: 10.2353/ajpath.2009.080599. Epub 2008 Dec 30.

Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity.小鼠体内轻度的线粒体解偶联会影响能量代谢、氧化还原平衡及寿命。

Aging Cell. 2008 Aug;7(4):552-60. doi: 10.1111/j.1474-9726.2008.00407.x. Epub 2008 Jul 10.

Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease.骨骼肌中的呼吸解偶联可延缓死亡并减少与年龄相关的疾病。

Cell Metab. 2007 Dec;6(6):497-505. doi: 10.1016/j.cmet.2007.10.010.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验