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Gene therapy to treat cardiovascular disease.

作者信息

Wolfram Julie A, Donahue J Kevin

机构信息

Department of Medicine, MetroHealth Campus of Case Western Reserve University, Cleveland, OH.

出版信息

J Am Heart Assoc. 2013 Aug 20;2(4):e000119. doi: 10.1161/JAHA.113.000119.

Abstract
摘要

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Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance.
Nat Med. 2013 Mar;19(3):305-12. doi: 10.1038/nm.3079. Epub 2013 Feb 10.
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HCN2/SkM1 gene transfer into canine left bundle branch induces stable, autonomically responsive biological pacing at physiological heart rates.
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Connexin43 gene transfer reduces ventricular tachycardia susceptibility after myocardial infarction.
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