Taghavi Nasim, Rajabi Moones, Mehrdad Leili, Sajjadi Samad
Department of Oral and Maxillofacial Pathology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Indian J Dent Res. 2013 Mar-Apr;24(2):220-4. doi: 10.4103/0970-9290.116688.
The aim of this study was to review cases of odontogenic tumors diagnosed in two pathology centers in Tehran, Iran, during a 10-year period.
Patients' records were seen at two teaching pathology Centre's of Shahid Beheshti University between the months of March 2000 to 2010 with histologic diagnosis of any type of odontogenic tumors. The records were analyzed for frequency, age, sex, site, as well as clinical, radiographic and histopathologic findings.
Of 30706 biopsies, 4767 (15.5%) cases were diagnosed as oral and maxillofacial lesions. Among these, 720 cases were tumoral with 188 (26.1%) cases of odontogenic tumors. Tumors with odontogenic epithelium origin formed 70.2% of total numbers of odontogenic tumors. Mixed odontogenic tumors and tumors of odontogenic ectomesenchyme comprised 12.2% and 17.5% of the cases respectively. Ameloblastoma, with a frequency of 62.2% was the most common tumor in this review which was followed by odontoma and odontogenic myxoma.
Although there are few studies on odontogenic tumors in literature, the comparison of our results with existing data shows significant differences in the distribution of tumors and age of patients, which may be due to ethnic features and geographic distribution of patients. Future studies on other ethnic groups are essential for further clarification of the findings in this research.
本研究旨在回顾伊朗德黑兰两个病理中心在10年期间诊断的牙源性肿瘤病例。
在2000年3月至2010年期间，查看了沙希德·贝赫什提大学两个教学病理中心的患者记录，这些记录的组织学诊断为任何类型的牙源性肿瘤。对记录进行了频率、年龄、性别、部位以及临床、影像学和组织病理学检查结果的分析。
在30706份活检中，4767例（15.5%）被诊断为口腔颌面部病变。其中，720例为肿瘤性病变，188例（26.1%）为牙源性肿瘤。牙源性上皮来源的肿瘤占牙源性肿瘤总数的70.2%。混合性牙源性肿瘤和牙源性外间充质肿瘤分别占病例的12.2%和17.5%。在本综述中，成釉细胞瘤的发生率为62.2%，是最常见的肿瘤，其次是牙瘤和牙源性黏液瘤。
尽管文献中关于牙源性肿瘤的研究较少，但将我们的结果与现有数据进行比较后发现，肿瘤分布和患者年龄存在显著差异，这可能归因于患者的种族特征和地理分布。对其他种族群体进行进一步研究对于进一步阐明本研究结果至关重要。
