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成釉细胞瘤的眼眶侵犯:关于一种罕见实体的系统评价

Orbital invasion of ameloblastoma: A systematic review apropos of a rare entity.

作者信息

Abtahi Mohammad-Ali, Zandi Alireza, Razmjoo Hassan, Ghaffari Sara, Abtahi Seyed-Mojtaba, Jahanbani-Ardakani Hamidreza, Kasaei Zahra, Kasaei-Koupaei Samira, Sajjadi Sepideh, Sonbolestan Seyed-Ali, Abtahi Seyed-Hossein

机构信息

Isfahan Eye Research Center, Feiz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Ophthalmology, Feiz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

J Curr Ophthalmol. 2017 Nov 6;30(1):23-34. doi: 10.1016/j.joco.2017.09.001. eCollection 2018 Mar.

DOI:10.1016/j.joco.2017.09.001
PMID:29564405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5859465/
Abstract

PURPOSE

Ameloblastoma is a non-encapsulated and slow-growing tumor with high recurrence rate. Orbital involvement by this neoplasm is an extremely rare entity. In this study, we present a systematic review on this situation along with clinical and paraclinical features of a case.

METHODS

An electronic search was conducted on major medical sources. Data of the cases in the literature in addition to our own case were extracted, summarized, and statistically analyzed.

RESULTS

A total of 36 other cases from 20 relevant studies were also reviewed. Review topics included epidemiology, clinical presentation, pathologic features, differential diagnosis, imaging, treatment, and prognosis. We provided a five-year history of a 50-year-old man with orbital/skull base invasion of plexiform maxillary ameloblastoma.

CONCLUSIONS

Maxillary ameloblastoma is a locally aggressive neoplasm, and physicians must be alert to the biologic behavior of this tumor to detect any invasion to critical structures such as orbit and cranium. Orbital ameloblastoma causes significant morbidity and mortality. We advocate meticulous patient follow-up with regular clinical examinations and paraclinical work-up for timely detection of any invasion or recurrence. The best must be done to avoid extensions by aggressive removal of maxillary ameloblastoma.

摘要

目的

成釉细胞瘤是一种无包膜、生长缓慢且复发率高的肿瘤。该肿瘤累及眼眶极为罕见。在本研究中,我们对这种情况进行了系统综述,并介绍了一例病例的临床和辅助检查特征。

方法

在主要医学资源上进行电子检索。除了我们自己的病例外,还提取、总结并统计分析了文献中病例的数据。

结果

还对来自20项相关研究的另外36例病例进行了综述。综述主题包括流行病学、临床表现、病理特征、鉴别诊断、影像学、治疗和预后。我们提供了一名50岁男性上颌丛状成釉细胞瘤侵犯眼眶/颅底的五年病史。

结论

上颌成釉细胞瘤是一种局部侵袭性肿瘤,医生必须警惕该肿瘤的生物学行为,以检测其对眼眶和颅骨等关键结构的任何侵犯。眼眶成釉细胞瘤会导致严重的发病率和死亡率。我们主张对患者进行细致的随访,定期进行临床检查和辅助检查,以便及时发现任何侵犯或复发情况。必须尽最大努力通过积极切除上颌成釉细胞瘤来避免其扩散。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/ffb390b37042/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/ddebcefd2ee7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/8bd1885557f1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/2ec66e4536de/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/a1f7c7a9eba3/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/77a013dfc89e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/7a99dfcf15cb/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/ffb390b37042/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/ddebcefd2ee7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/8bd1885557f1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/2ec66e4536de/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/a1f7c7a9eba3/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/77a013dfc89e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/7a99dfcf15cb/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/532d/5859465/ffb390b37042/gr7.jpg

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Ameloblastoma: A Review of Recent Molecular Pathogenetic Discoveries.成釉细胞瘤:近期分子发病机制研究进展综述
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Maxillary Ameloblastoma: A Review With Clinical, Histological and Prognostic Data of a Rare Tumor.上颌骨造釉细胞瘤:一种罕见肿瘤的临床、组织学和预后数据的综述。
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