一种方便的筛选产碳青霉烯酶铜绿假单胞菌的方法。
A convenient method to screen for carbapenemase-producing Pseudomonas aeruginosa.
机构信息
Centre National de Référence de la Résistance aux Antibiotiques, Centre Hospitalier Régional Universitaire de Besançon, Besançon, France.
出版信息
J Clin Microbiol. 2013 Nov;51(11):3846-8. doi: 10.1128/JCM.01299-13. Epub 2013 Aug 21.
Abstract
A combined-disk method using imipenem and cloxacillin was evaluated to discriminate between carbapenemase-producing (n = 56) and nonproducing (n = 62) strains of Pseudomonas aeruginosa. With a cloxacillin load of 4,000 μg/disk, this very simple method showed a sensitivity and a specificity of 100%, irrespective of the type of carbapenemase produced.
摘要
采用亚胺培南-克拉维酸联合药敏纸片法检测 56 株产碳青霉烯酶铜绿假单胞菌和 62 株非产碳青霉烯酶铜绿假单胞菌，克拉维酸负荷量为 4000μg/片，该方法非常简单，检测结果显示产碳青霉烯酶的检测敏感性和特异性均为 100%，与碳青霉烯酶的类型无关。
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