Department of Psychiatry, Kocaeli Derince Training and Research Hospital , Kocaeli , Turkey .
Gynecol Endocrinol. 2013 Dec;29(12):1055-8. doi: 10.3109/09513590.2013.829447. Epub 2013 Aug 23.
Puberty and adolescence are important periods about mental health, particularly for women. Relationship between age of menarche, psychiatric complaints during adolescence and family stories of psychiatric disorders are investigated.
The study is conducted with 61 patients with schizophrenia, 35 patients with bipolar affective disorder, 40 patients with depressive disorder and 60 healthy control subjects. All subjects were evaluated with SCID-I and questionnaire fit for the aim of the study was fulfilled.
Bipolar affective disorder had a stronger relationship with menarche, psychiatric problems during adolescence were related with early onset of illness in schizophrenia and bipolar groups. Family story of psychiatric illness was related with psychological problems during puberty in schizophrenia group.
This study underlies the puberty and adolescence period for psychiatric illness. An integrative clinical approach is suggested while examining the psychiatric illness at the basis of engaged roles of hormonal effects of menarche, social effect of puberty psychiatric complaints and genetical and psychosocial burden of family story of illness.
青春期是心理健康的重要时期，尤其是对女性而言。本研究旨在探讨初潮年龄、青春期精神问题与家族精神病史之间的关系。
本研究纳入了 61 例精神分裂症患者、35 例双相情感障碍患者、40 例抑郁症患者和 60 名健康对照者。所有受试者均采用 SCID-I 进行评估，并填写适合研究目的的问卷。
双相情感障碍与初潮年龄的相关性更强，精神疾病在青春期出现的问题与精神分裂症和双相障碍组的发病年龄早有关。家族精神病史与精神分裂症组青春期心理问题有关。
本研究强调了青春期对精神疾病的重要性。在对精神疾病进行检查时，建议采用综合临床方法，考虑初潮时的激素影响、青春期精神问题的社会影响以及家族病史的遗传和心理社会负担等因素。
