ViroClinics BioSciences BV, Rotterdam, The Netherlands.
Emerg Infect Dis. 2013;19(9):1511-3. doi: 10.3201/eid1909.130404.
To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.
为了鉴定未知的人类病毒,我们通过病毒宏基因组学分析了马拉维不明原因截瘫患者的血清和脑脊液样本。鉴定出了一种新型环状病毒种,随后分别在 15%和 10%的血清和脑脊液样本中发现了该病毒。这些数据扩展了我们对环状病毒多样性和嗜性的认识。