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影响土耳其伊斯坦布尔青少年哮喘患病率的风险因素。

Risk factors affecting asthma prevalence in adolescents living in Istanbul, Turkey.

作者信息

Akcay A, Tamay Z, Hocaoglu A B, Ergin A, Guler N

机构信息

Liv Hospital, Department of Pediatrics, Division of Pediatric Allergy, Istanbul, Turkey.

Istanbul University, Istanbul School of Medicine, Department of Pediatrics, Division of Pediatric Allergy, Istanbul, Turkey.

出版信息

Allergol Immunopathol (Madr). 2014 Sep-Oct;42(5):449-58. doi: 10.1016/j.aller.2013.05.005. Epub 2013 Aug 19.

DOI:10.1016/j.aller.2013.05.005
PMID:23969072
Abstract

BACKGROUND

Asthma is one of the most important diseases of childhood. The aim of this study was to evaluate the prevalence of asthma symptoms and risk factors affecting asthma.

METHODS

In a cross-sectional study design, 9991 children, aged 13-14 years in 61 primary schools in 32 districts of Istanbul were evaluated. Asthma prevalence among the children was assessed using the ISAAC protocol.

RESULTS

In our study, a total of 10,894 questionnaires were distributed to 13-14 years old children, and of these 9991 questionnaires were suitable for analysis with an overall response rate of 91.7%. The rates of wheeze ever, wheezing in last 12 months and lifetime doctor diagnosed asthma prevalence were 17.4%, 9.0%, and 11.8%, respectively. There were 4746 boys (47.9%) and 5166 girls (52.1%) with M/F ratio of 0.92. Atopic family history, fewer than three siblings living at home, tonsillectomy or adenoidectomy history, consumption of fermented foods, mixed pickles, margarine and meat were found to be associated with an increased asthma risk. Use of paracetamol in the last 12 months, consumption of fruit and animal fats acted as a protective factor against asthma. The Mediterranean-style diet was not associated with the prevalence of asthma.

CONCLUSIONS

Lifetime doctor diagnosed asthma prevalence was found to be 11.8% in 13-14 year olds. History of tonsillectomy and/or adenoidectomy and consumption of fermented foods, mixed pickles, margarine and meat may increase the symptoms of asthma. Usage of paracetamol and consumption of animal fats may be investigated as a protective factor against asthma.

摘要

背景

哮喘是儿童最重要的疾病之一。本研究的目的是评估哮喘症状的患病率以及影响哮喘的危险因素。

方法

采用横断面研究设计,对伊斯坦布尔32个区61所小学的9991名13 - 14岁儿童进行评估。使用国际儿童哮喘及过敏研究(ISAAC)方案评估儿童中的哮喘患病率。

结果

在我们的研究中,共向13 - 14岁儿童发放了10894份问卷,其中9991份问卷适合分析,总体应答率为91.7%。曾经喘息、过去12个月内喘息以及一生中有医生诊断哮喘的患病率分别为17.4%、9.0%和11.8%。有4746名男孩(47.9%)和5166名女孩(52.1%),男/女比例为0.92。发现特应性家族史、家中同住兄弟姐妹少于三人、扁桃体切除术或腺样体切除术史、食用发酵食品、混合泡菜、人造黄油和肉类与哮喘风险增加有关。过去12个月内使用对乙酰氨基酚、食用水果和动物脂肪是预防哮喘的保护因素。地中海式饮食与哮喘患病率无关。

结论

在13 - 14岁儿童中,一生中有医生诊断哮喘的患病率为11.8%。扁桃体切除术和/或腺样体切除术史以及食用发酵食品、混合泡菜、人造黄油和肉类可能会增加哮喘症状。对乙酰氨基酚的使用和动物脂肪的食用可作为预防哮喘的保护因素进行研究。

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