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地中海饮食依从性对儿童哮喘和过敏是否具有保护作用?系统评价。

Does Adherence to the Mediterranean Diet Have a Protective Effect against Asthma and Allergies in Children? A Systematic Review.

机构信息

Department of Nursing, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Third Department of Pediatrics, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.

出版信息

Nutrients. 2022 Apr 13;14(8):1618. doi: 10.3390/nu14081618.

Abstract

Dietary pattern may potentially impact on the pathogenesis of asthma and allergies. The Mediterranean Diet (MD) has significant health benefits due to its antioxidant and anti-inflammatory properties. The aim of this systematic review was to investigate the effectiveness of adherence to the MD against asthma and allergies in childhood. Hence, a systematic literature search was conducted on PubMed, ESBCO (Cinahl), Scopus, and the Cochrane Library databases up to 26 January 2022. The total number of articles obtained, after the initial search on the databases was conducted, was 301. Twelve studies were included, after the removal of duplicates and screening for eligibility. Our findings indicated a protective role of the MD against childhood asthma, but they also imply that the MD probably does not affect the development of allergies. Nevertheless, the heterogeneity and limitations of the studies highlight the need for randomized controlled trials that will focus on the pediatric population and hopefully provide more robust evidence.

摘要

饮食模式可能潜在地影响哮喘和过敏的发病机制。地中海饮食(Mediterranean Diet,MD)由于其抗氧化和抗炎特性,具有显著的健康益处。本系统评价的目的是研究遵守 MD 对儿童哮喘和过敏的有效性。因此,对 PubMed、ESBCO(Cinahl)、Scopus 和 Cochrane 图书馆数据库进行了系统的文献检索,检索时间截至 2022 年 1 月 26 日。在对数据库进行初步搜索后,总共获得了 301 篇文章。在去除重复项并进行资格筛选后,纳入了 12 项研究。我们的研究结果表明 MD 对儿童哮喘具有保护作用,但也表明 MD 可能不会影响过敏的发展。然而,研究的异质性和局限性突出表明需要进行随机对照试验,这些试验将重点关注儿科人群,并有望提供更有力的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a539/9031000/4a5b21c46788/nutrients-14-01618-g001.jpg

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