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慢性过量饮酒与男性生育能力:一例关于可逆性无精子症的病例报告及文献综述

Chronic excessive alcohol consumption and male fertility: a case report on reversible azoospermia and a literature review.

作者信息

Guthauser Bruno, Boitrelle Florence, Plat Arnaud, Thiercelin Nicolas, Vialard Francois

机构信息

Corresponding author: Centre Hospitalier de Dreux, 44 Avenue du Président Kennedy, F-28100 Dreux, France.

出版信息

Alcohol Alcohol. 2014 Jan-Feb;49(1):42-4. doi: 10.1093/alcalc/agt133. Epub 2013 Aug 21.

Abstract

AIMS

The aim of this work was to report on a heavy drinker whose azoospermia was reversed after alcohol withdrawal. We also review the literature on links between alcohol consumption and azoospermia.

METHOD

This study is a clinical case report and a literature review.

RESULTS

Two years after alcohol withdrawal, a child was born following assisted reproduction technique. Excessive alcohol consumption (i.e. more than 60 g a day) is strongly associated with azoospermia and this condition may be reversible after alcohol withdrawal.

CONCLUSIONS

Testicular biopsies should be countra-indicated for heavy drinkers, and in order to increase the chances of obtaining a pregnancy, alcohol abstinence should be encouraged in male with low-to-moderate alcohol intakes.

摘要

目的

本研究旨在报告一例重度饮酒者在戒酒后代偿性恢复无精子症的病例。我们还回顾了饮酒与无精子症之间联系的相关文献。

方法

本研究为临床病例报告及文献综述。

结果

戒酒两年后,通过辅助生殖技术诞生了一名婴儿。过量饮酒(即每天超过60克)与无精子症密切相关,且这种情况在戒酒后可能是可逆的。

结论

对于重度饮酒者,应禁止进行睾丸活检;为提高受孕几率,对于低至中度饮酒的男性,应鼓励其戒酒。

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