Bhardwaj Ashok, Kumar Dinesh, Raina Sunil Kumar, Bansal Pardeep, Bhushan Satya, Chander Vishav
Department of Community Medicine, Dr. Rajendra Prasad Government Medical College, Kangra, Himachal Pradesh 176001, India.
Anemia. 2013;2013:959605. doi: 10.1155/2013/959605. Epub 2013 Jul 22.
Coexistence of folic acid and vitamin B12 deficiency has been observed among adolescents with iron deficiency anemia, but limited evidence is available from India. So, a rapid assessment was done to study the prevalence of iron, folic acid, and vitamin B12 deficiency among adolescent males and females in northern Himalayan state in India. Methods. Total 885 (female: 60.9%) adolescents (11 to 19 completed years) were surveyed from 30-cluster village from two community development blocks of Himachal Pradesh. Serum ferritin, folic acid, and vitamin B12 were estimated among randomly selected 100 male and 100 female adolescents. Results. Under-nutrition (BMI < 18.5 kg/m(2)) was observed among 68.9% of adolescents (male: 67.1%; female: 70.7; P = 0.29). Anemia was observed to be prevalent among 87.2% males and 96.7% females (P = 0.00). Mild form of anemia was observed to be the most common (53.9%) form followed by moderate (29.7%) anemia. Strikingly, it was found that all the adolescents were deficient in vitamin B12 and none of the adolescents was observed to be deficient in folic acid. Conclusion. Among both male and female adolescents anemia with vitamin B12 deficiency was observed to be a significant public health problem. Folic acid deficiency was not observed as a problem among surveyed adolescents.
在缺铁性贫血的青少年中已观察到叶酸和维生素B12缺乏并存的情况,但来自印度的相关证据有限。因此,开展了一项快速评估,以研究印度喜马拉雅邦北部青少年男性和女性中铁、叶酸和维生素B12缺乏的患病率。方法。从喜马偕尔邦两个社区发展区的30个集群村庄中调查了总共885名青少年(11至19周岁,已完成相应年龄)(女性占60.9%)。在随机选取的100名男性和100名女性青少年中测定血清铁蛋白、叶酸和维生素B12。结果。68.9%的青少年存在营养不良(体重指数<18.5kg/m²)(男性为67.1%;女性为70.7%;P=0.29)。观察到贫血在87.2%的男性和96.7%的女性中普遍存在(P=0.00)。轻度贫血被观察到是最常见的(53.9%)形式,其次是中度贫血(29.7%)。令人惊讶的是,发现所有青少年都缺乏维生素B12,且未观察到有青少年缺乏叶酸。结论。在青少年男性和女性中,贫血伴维生素B12缺乏被观察到是一个重大的公共卫生问题。在所调查的青少年中未发现叶酸缺乏是一个问题。