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[1980 - 1988年在比尔森妇女诊所对不育夫妇研究的精子凝集抗体]

[Sperm agglutination antibodies studied in infertile couples at the Women's Clinic in Plzen 1980-1988].

作者信息

Ulcová-Gallová Z, Kotál L, Macků F, Zavázal V

机构信息

Gynek.-porod. klinika LF KU, Plzen.

出版信息

Cesk Gynekol. 1990 Jun;55(5):327-32.

PMID:2397505
Abstract

The authors assessed sperm-agglutination antibodies in infertile couples in 1980-1988, using the Kibrick test: in sera from 699 female patients, a positive result was found in 142 (20%) women, in sera from 352 men, in 6 (1.7%) sperm-agglutination antibodies were detected. Using the microagglutination test, they examined sera of 3501 sterile women; in 273 (6.8%) they found sperm agglutination up to 1:16, above titre 1:32 in 12 (0.4%) of the patients. Using the same test, they examined sera of 2803 men and found sperm-agglutination up to 1:16 in 21 (0.7%) and above 1:32 in 6 (0.3%). The most frequent type of sperm agglutination is aggregation of the heads; aggregation by tails or mixed agglutination are less frequent. In 3252 sterile women where no sperm-agglutination antibodies were found Kremer's test was negative in 1145 patients. The authors analyzed in 196 sterile women the ovulation mucus by the microagglutination test and found a high anti-spermatozoidal activity in 24 (12%) women. Concurrently an indirect MAR test was made. Antibodies against sperm cells were found in 24 (12.2%) of specimens in sIgA, in 8 (4.1%) in IgG, in 2 (2%) in IgM and in one sample (0.5%) in IgE. The indirect MAR-test in sera of 325 sterile women revealed a predominance of anti-spermatozoidal antibodies in IgG, in men in IgA. In seminal plasma the authors detected antibodies against sperm cells in sIgA. In seminal plasma the authors detected antibodies against sperm cells in sIgA and IgE.

摘要

作者于1980年至1988年期间,使用基布里克试验对不育夫妇的精子凝集抗体进行了评估:在699名女性患者的血清中,142名(20%)女性检测结果呈阳性;在352名男性的血清中,检测到6名(1.7%)存在精子凝集抗体。使用微量凝集试验,他们检测了3501名不育女性的血清;其中273名(6.8%)患者的精子凝集效价达到1:16,12名(0.4%)患者的效价高于1:32。使用相同试验,他们检测了2803名男性的血清,发现21名(0.7%)的精子凝集效价达到1:16,6名(0.3%)高于1:32。最常见的精子凝集类型是头部聚集;尾部聚集或混合凝集则较少见。在3252名未检测到精子凝集抗体的不育女性中,1145名患者的克雷默试验呈阴性。作者对196名不育女性的排卵黏液进行了微量凝集试验分析,发现24名(12%)女性具有较高的抗精子活性。同时进行了间接MAR试验。在标本中,sIgA中24名(12.2%)检测到抗精子细胞抗体,IgG中8名(4.1%),IgM中2名(2%),IgE中1名(0.5%)。对325名不育女性血清进行的间接MAR试验显示,IgG中抗精子抗体占优势,男性中则以IgA为主。在精浆中,作者检测到sIgA中的抗精子细胞抗体。在精浆中,作者检测到sIgA和IgE中的抗精子细胞抗体。

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[Sperm agglutination antibodies studied in infertile couples at the Women's Clinic in Plzen 1980-1988].[1980 - 1988年在比尔森妇女诊所对不育夫妇研究的精子凝集抗体]
Cesk Gynekol. 1990 Jun;55(5):327-32.
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