Ulcová-Gallová Z
Department of Obstetrics and Gynaecology, Charles University of Pilsen, Plzen, Czechoslovakia.
Int J Fertil Menopausal Stud. 1994 May-Jun;39(3):185-91.
To compare levels of sperm-agglutinating antibodies in male and female sera, cervical ovulatory mucus, and seminal plasma by two different tests.
408 women and 404 men with long-lasting unexplained infertility and recurrent IVF failure were immunologically examined. Tray agglutination and mixed antiglobulin reaction tests were used for the comparison of sperm-agglutinating antibodies in sera, in ovulatory cervical mucus, and in seminal plasma.
High secretory IgA positivity predominated in seminal plasma in 16 (3.9%) of infertile men and in cervical ovulatory mucus in 114 (27.9%) of infertile women. Positivity in two sperm antibodies together, in IgG and IgA, and IgM and IgE was also observed. Immunological anti-sperm antibodies in sera indicate high levels of sperm antibodies in IgG and IgM.
Sperm immunoglobulin specification is important for therapeutic influence upon immunocompetent cells.
通过两种不同检测方法比较男性和女性血清、宫颈排卵期黏液及精浆中精子凝集抗体水平。
对408名女性和404名男性进行免疫学检查，这些患者患有长期不明原因不孕且反复体外受精失败。采用托盘凝集试验和混合抗球蛋白反应试验比较血清、排卵期宫颈黏液及精浆中的精子凝集抗体。
16名（3.9%）不育男性的精浆中及114名（27.9%）不育女性的宫颈排卵期黏液中，分泌型IgA高阳性占主导。还观察到IgG和IgA、IgM和IgE两种精子抗体同时呈阳性。血清中的免疫抗精子抗体表明IgG和IgM中精子抗体水平较高。
精子免疫球蛋白的特异性对于对免疫活性细胞的治疗影响很重要。
