Institute of Developmental Genetics, Heinrich Heine University, D-40225 Düsseldorf, Germany.
J Exp Bot. 2013 Dec;64(17):5237-41. doi: 10.1093/jxb/ert245. Epub 2013 Aug 24.
Due to their rigid cell walls, plant cells can only communicate with each other either by symplastic transport of diverse non-cell autonomous signalling molecules via plasmodesmata (PDs) or by endo- and exocytosis of signalling molecules via the extracellular apoplastic space. PDs are plasma membrane-lined channels spanning the cell wall between neighbouring cells, allowing the exchange of molecules by symplastic movement through them. This review focuses on developmental decisions that are coordinated by short- and long-distance communication of cells via PDs. We propose a model combining both apoplastic and symplastic signalling events via secreted ligands and their PD-localized receptor kinases which gate the symplastic transport of information molecules through PDs. Cell communities can thus coordinate cell-fate decisions non-cell autonomously by connecting or disconnecting symplastic subdomains. Here we concentrate on the establishment of such subdomains in the plant's primary meristems that serve to maintain long-lasting stem cell populations in the shoot and root apical meristems, and discuss how apoplastic signalling via transport of information molecules through PDs is integrated with symplastic feedback signalling events.
由于植物细胞具有刚性细胞壁，因此它们只能通过胞质运输通过胞间连丝 (PD) 的各种非细胞自主信号分子或通过信号分子的内吞作用和外排作用通过细胞外质空间进行相互通信。PD 是跨细胞间隙排列在相邻细胞之间的质膜通道，允许通过它们的胞质运动交换分子。这篇综述重点介绍了通过 PD 进行短距离和长距离细胞通信协调的发育决策。我们提出了一个模型，该模型通过分泌配体及其 PD 定位的受体激酶将质外体和胞质信号事件结合在一起，从而通过 PD 控制信息分子的胞质运输。因此，细胞群体可以通过连接或断开胞质亚域来非自主地协调细胞命运决定。在这里，我们集中讨论在植物初生分生组织中建立这种亚域的问题，这些亚域用于维持茎和根顶端分生组织中持久的干细胞群体，并讨论通过 PD 运输信息分子的质外体信号如何与胞质反馈信号事件整合。
