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复发性喘息发作的危险因素评估。

Evaluation of risk factors for recurrent wheezing episodes.

作者信息

Bozaykut Abdulkadir, Paketci Ahu, Sezer Rabia Gonul, Paketci Cem

机构信息

Zeynep Kamil Maternity and Childrens' Disease Training and Research Hospital, Department of Pediatrics, Uskudar 34668, Istanbul, Turkey.

出版信息

J Clin Med Res. 2013 Oct;5(5):395-400. doi: 10.4021/jocmr1543w. Epub 2013 Aug 5.

DOI:10.4021/jocmr1543w
PMID:23976913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3748665/
Abstract

BACKGROUND

We aimed to evaluate the risk factors for recurrent wheezing in patients diagnosed with acute bronchiolitis.

METHOD

From 2009 to 2011, 500 patients from the pediatric clinics, with first attack of acute bronchiolitis were included in this prospective study. Each patient's age, gender, birth weight, duration of breastfeeding, family history of atopy and asthma, smoking exposure, source of heating in the house, the presence of pets, any history of chronic disease have been questioned. The patients were followed for a duration of 12 - 24 months.

RESULTS

In this study, 39% (n = 195) of the cases were female and 61% (n = 305) were male, with a median age of 3 months old. Male gender, low birth weight (< 2,500 g), low gestational age (< 37 weeks), breastfeeding of less than 6 months, congenital heart disease, family history of atopy, asthma, smoking exposure, stove warming, was found as significant risk factors for recurrent wheezing, however, presence of pets at home was found to be a protective factor.

CONCLUSIONS

Informing parents about the risk factors such as exposure to cigarette smoke, heating mode, duration of breastfeeding can significantly decrease recurrent episodes of wheezing.

摘要

背景

我们旨在评估诊断为急性细支气管炎的患者反复喘息的危险因素。

方法

2009年至2011年,本前瞻性研究纳入了500例来自儿科门诊的首次发作急性细支气管炎的患者。询问了每位患者的年龄、性别、出生体重、母乳喂养时间、特应性和哮喘家族史、吸烟暴露情况、家中供暖来源、是否有宠物以及任何慢性病病史。对患者进行了12至24个月的随访。

结果

在本研究中,39%(n = 195)的病例为女性,61%(n = 305)为男性,中位年龄为3个月。男性、低出生体重(<2500克)、低胎龄(<37周)、母乳喂养少于6个月、先天性心脏病、特应性家族史、哮喘、吸烟暴露、炉灶取暖被发现是反复喘息的重要危险因素,然而,家中有宠物被发现是一个保护因素。

结论

告知家长诸如接触香烟烟雾、供暖方式、母乳喂养时间等危险因素可显著减少喘息的反复发作。

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