麻醉期间的胃液分泌及其受甲硫米特和其他药物的抑制作用。
Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.
作者信息
Schachter M, Karpinski E, Haines V
出版信息
Experientia. 1975 Aug 15;31(8):964-5. doi: 10.1007/BF02358879.
PMID:239857
Abstract
The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide.
摘要
组胺H2受体拮抗剂甲硫米特可抑制慢性植入胃插管的犬在水合氯醛-乌拉坦麻醉下产生的胃酸分泌。阿托品和六甲铵也可抑制这种分泌。甲硫米特还能阻断清醒犬迷走神经源性的“自发性”胃酸分泌。
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