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麻醉期间的胃液分泌及其受甲硫米特和其他药物的抑制作用。

Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.

作者信息

Schachter M, Karpinski E, Haines V

出版信息

Experientia. 1975 Aug 15;31(8):964-5. doi: 10.1007/BF02358879.

DOI:10.1007/BF02358879
PMID:239857
Abstract

The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide.

摘要

组胺H2受体拮抗剂甲硫米特可抑制慢性植入胃插管的犬在水合氯醛-乌拉坦麻醉下产生的胃酸分泌。阿托品和六甲铵也可抑制这种分泌。甲硫米特还能阻断清醒犬迷走神经源性的“自发性”胃酸分泌。

相似文献

1
Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.麻醉期间的胃液分泌及其受甲硫米特和其他药物的抑制作用。
Experientia. 1975 Aug 15;31(8):964-5. doi: 10.1007/BF02358879.
2
Effect of the H2-receptor antagonists (burimamide and metiamide) on gastric secretion stimulated by histamine and its methyl derivatives.H2受体拮抗剂(布立马胺和甲硫米特)对组胺及其甲基衍生物刺激的胃酸分泌的影响。
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The effects of metiamide on gastric secretion and stress ulceration in rats.甲硫米特对大鼠胃液分泌及应激性溃疡的影响。
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Metiamide and stimulated acid secretion from the isolated non-distended and distended mouse stomach.甲硫米特与离体未扩张和扩张小鼠胃的刺激酸分泌。
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The effects of somatostatin and metiamide on tachyphylaxis of pentagastrin stimulated gastric acid and pepsin secretion in the conscious cat.生长抑素和甲硫咪特对清醒猫中五肽胃泌素刺激的胃酸和胃蛋白酶分泌快速耐受的影响。
J Physiol. 1977 Apr;266(3):801-17. doi: 10.1113/jphysiol.1977.sp011794.

引用本文的文献

1
The effect of anaesthesia on pentagastrin stimulated gastric acid secretion in the cat.麻醉对猫五肽胃泌素刺激胃酸分泌的影响。
J Physiol. 1978 Jan;274:1-8. doi: 10.1113/jphysiol.1978.sp012129.

本文引用的文献

1
THE ABNORMAL FUNCTIONING OF THE GASTRIC SECRETORY MECHANISM AS A POSSIBLE FACTOR IN THE PATHOGENESIS OF PEPTIC ULCER.胃分泌机制的异常运作作为消化性溃疡发病机制中的一个可能因素。
Can Med Assoc J. 1938 May;38(5):421-9.
2
Anesthesia and gastric secretion.麻醉与胃液分泌。
Am J Physiol. 1949 Feb;156(2):248-55. doi: 10.1152/ajplegacy.1949.156.2.248.
3
Histamine and gastric secretion: a later look, 1955-1965.组胺与胃液分泌:回顾,1955 - 1965年
Fed Proc. 1965 Nov-Dec;24(6):1311-21.
4
Definition and antagonism of histamine H 2 -receptors.组胺H2受体的定义与拮抗作用。
Nature. 1972 Apr 21;236(5347):385-90. doi: 10.1038/236385a0.
5
Actions of metiamide, an H2-histamine receptor antagonist, on gastric H+ and pepsin secretion in dogs.H2组胺受体拮抗剂甲硫米特对犬胃H⁺和胃蛋白酶分泌的作用。
Gastroenterology. 1974 Jul;67(1):93-9.
6
Inhibition of acid secretion in dog by metiamide, a histamine antagonist acting on H2 receptors.甲硫米特(一种作用于H2受体的组胺拮抗剂)对犬胃酸分泌的抑制作用。
Gastroenterology. 1974 Apr;66(4):517-21.
7
Metiamide--an orally active histamine H2-receptor antagonist.甲硫米特——一种口服有效的组胺H2受体拮抗剂。
Agents Actions. 1973 Oct;3(3):133-7. doi: 10.1007/BF01965723.