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Caveats for using shock tube in blast-induced traumatic brain injury research.

作者信息

Chen Yun, Constantini Shlomi

机构信息

BrightstarTech, Inc. , Clarksburg, MD, USA.

出版信息

Front Neurol. 2013 Aug 26;4:117. doi: 10.3389/fneur.2013.00117. eCollection 2013.

DOI:10.3389/fneur.2013.00117
PMID:23986741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3752771/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc2e/3752771/eef5db59ef2c/fneur-04-00117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc2e/3752771/eef5db59ef2c/fneur-04-00117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc2e/3752771/eef5db59ef2c/fneur-04-00117-g001.jpg

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Note: A table-top blast driven shock tube.注意：一种台式爆炸驱动激波管。
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Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction.神经元的机械损伤会导致 tau 蛋白向树突棘的异常定位和 tau 依赖性的突触功能障碍。

本文引用的文献

1
Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.爆炸暴露的退伍军人慢性创伤性脑病和爆炸神经创伤小鼠模型。
Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716.
2
Oxy-acetylene driven laboratory scale shock tubes for studying blast wave effects.用于研究冲击波效应的氧乙炔驱动实验室规模激波管。
Rev Sci Instrum. 2012 Apr;83(4):045111. doi: 10.1063/1.3702803.
3
Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury.
Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29069-29079. doi: 10.1073/pnas.2008306117. Epub 2020 Nov 2.
4
Behavioral Deficits in Animal Models of Blast Traumatic Brain Injury.爆炸创伤性脑损伤动物模型中的行为缺陷
Front Neurol. 2020 Sep 4;11:990. doi: 10.3389/fneur.2020.00990. eCollection 2020.
5
Modelling traumatic brain injury and posttraumatic epilepsy in rodents.在啮齿类动物中建立创伤性脑损伤和外伤性癫痫模型。
Neurobiol Dis. 2019 Mar;123:8-19. doi: 10.1016/j.nbd.2018.08.007. Epub 2018 Aug 16.
6
Towards Traceable Transient Pressure Metrology.迈向可溯源的瞬态压力计量学。
Metrologia. 2018 Apr;55(2):275-283. doi: 10.1088/1681-7575/aaad1b. Epub 2018 Mar 13.
7
Combination Therapy for Multi-Target Manipulation of Secondary Brain Injury Mechanisms.联合治疗：多靶点调控二次脑损伤机制
Curr Neuropharmacol. 2018;16(4):484-504. doi: 10.2174/1570159X15666170828165711.
8
Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration.Exendin-4 可减轻爆炸创伤性脑损伤引起的认知障碍、突触素丧失和体外创伤性脑损伤引起的海马细胞变性。
Sci Rep. 2017 Jun 16;7(1):3735. doi: 10.1038/s41598-017-03792-9.
9
Acute death of astrocytes in blast-exposed rat organotypic hippocampal slice cultures.暴露于爆炸环境的大鼠器官型海马切片培养物中星形胶质细胞的急性死亡。
PLoS One. 2017 Mar 6;12(3):e0173167. doi: 10.1371/journal.pone.0173167. eCollection 2017.
10
Blast waves from detonated military explosive reduce GluR1 and synaptophysin levels in hippocampal slice cultures.引爆的军用炸药产生的冲击波会降低海马切片培养物中GluR1和突触素的水平。
Exp Neurol. 2016 Dec;286:107-115. doi: 10.1016/j.expneurol.2016.10.002. Epub 2016 Oct 5.
有身体防护的大鼠的爆炸暴露主要表现为弥漫性轴索损伤。
J Neurotrauma. 2011 Jun;28(6):947-59. doi: 10.1089/neu.2010.1540.
4
Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research.原发性爆炸冲击性脑损伤的机制：冲击波研究的新视角。
J Neurotrauma. 2011 Jun;28(6):1101-19. doi: 10.1089/neu.2010.1442. Epub 2011 May 5.